The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-P: 1/100 - 1/500.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with Frozen Sections.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
Expressed in a number of tissues. Abundant in testis.
Belongs to the DNA polymerase type-X family. Contains 1 BRCT domain.
Phosphorylated upon DNA damage, probably by ATM or ATR.