The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
追加情報IHC-P: 1/100 - 1/500.
Epitope exposure with citrate buffer will enhance staining.
Likely to work with Frozen Sections.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
機能Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
組織特異性Expressed in a number of tissues. Abundant in testis.
配列類似性Belongs to the DNA polymerase type-X family. Contains 1 BRCT domain.
翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.