Anti-DNA Polymerase lambda 抗体 (ab82919)

製品の概要

  • 製品名Anti-DNA Polymerase lambda antibody
    DNA Polymerase lambda 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to DNA Polymerase lambda
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide, corresponding to a region within internal sequence amino acids 525 - 574 (SLSEHALSTAVVRNTHGCKVGPGRVLPTPTEKDVFRLLGLPYREPAERD W) of Human DNA Polymerase lambda, (NP_037406)

  • ポジティブ・コントロール
    • Fetal brain lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab82919 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 63 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay: 1/12500.

ターゲット情報

  • 機能Repair polymerase. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
  • 組織特異性Expressed in a number of tissues. Abundant in testis.
  • 配列類似性Belongs to the DNA polymerase type-X family.
    Contains 1 BRCT domain.
  • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BETA N antibody
    • BETAN antibody
    • DNA directed DNA polymerase lambda antibody
    • DNA polymerase beta 2 antibody
    • DNA polymerase beta-2 antibody
    • DNA polymerase kappa antibody
    • DNA polymerase kappa DNA polymerase beta N antibody
    • DNA polymerase lambda antibody
    • DNA polymerase lamda2 antibody
    • DPOLL_HUMAN antibody
    • EC 2.7.7.7,EC 4.2.99. antibody
    • FLJ46002 antibody
    • OTTHUMP00000020321 antibody
    • OTTHUMP00000020323 antibody
    • OTTHUMP00000059179 antibody
    • Pol beta2 antibody
    • POL KAPPA antibody
    • Pol Lambda antibody
    • POLKAPPA antibody
    • POLL antibody
    • Polymerase DNA directed lambda antibody
    see all

Anti-DNA Polymerase lambda antibody 画像

  • Anti-DNA Polymerase lambda antibody (ab82919) at 1 µg/ml + fetal brain lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 63 kDa
    Observed band size : 63 kDa

Anti-DNA Polymerase lambda antibody (ab82919) 使用論文

ab82919 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"