Anti-DNA Polymerase beta (di methyl R152) 抗体 (ab93672)

製品の概要

  • 製品名
    Anti-DNA Polymerase beta (di methyl R152) antibody
    DNA Polymerase beta 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to DNA Polymerase beta (di methyl R152)
  • アプリケーション
    適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Recombinant fragment
    交差が予測される動物種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to the N terminal residues of Human DNA Polymerase beta.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab93672 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 38 kDa. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA 1/2000 - 1/5000.

ターゲット情報

  • 機能
    Repair polymerase. Conducts "gap-filling" DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
  • 配列類似性
    Belongs to the DNA polymerase type-X family.
  • ドメイン
    Residues 239-252 form a flexible loop which appears to affect the polymerase fidelity.
  • 翻訳後修飾
    Methylation by PRMT6 stimulates the polymerase activity by enhancing DNA binding and processivity.
  • 細胞内局在
    Nucleus, Cytoplasm
  • Information by UniProt
  • 参照データベース
  • 別名
    • DNA directed DNA polymerase beta antibody
    • DNA pol beta antibody
    • DNA polymerase beta antibody
    • DNA polymerase beta subunit antibody
    • DPOLB_HUMAN antibody
    • MGC125976 antibody
    • Pol B antibody
    • Pol beta antibody
    • POLB antibody
    • Polymerase (DNA directed) beta antibody
    see all

プロトコール

参考文献

ab93672 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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