Anti-DNA Polymerase beta (di methyl R152) 抗体 (ab93672)

製品の概要

• 製品名Anti-DNA Polymerase beta (di methyl R152) antibody
  DNA Polymerase beta 一次抗体 製品一覧
• 製品の詳細
  Rabbit polyclonal to DNA Polymerase beta (di methyl R152)
• アプリケーション適用あり: WB, ELISAmore details
• 種交差性
  交差種: Recombinant fragment
  交差が予測される動物種: Mouse, Rat, Human
• 免疫原

  Synthetic peptide corresponding to the N terminal residues of Human DNA Polymerase beta.

製品の特性

• 製品の状態Liquid
• 保存方法Shipped at 4°C. Store at -20ºC.
• バッファーPreservative: 0.01% Sodium Azide
  Constituents: 50% Glycerol, PBS
• Concentration information loading...
• 精製度Immunogen affinity purified
• 特記事項（精製）Purity >90%
• ポリ/モノポリクローナル
• アイソタイプIgG
• 研究分野
  • Epigenetics and Nuclear Signaling
  • DNA / RNA
  • DNA Damage & Repair
  • Base Excision Repair

  • Epigenetics and Nuclear Signaling
  • DNA / RNA
  • DNA Synthesis
  • DNA Polymerases

関連製品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

アプリケーション

ターゲット情報

• 機能Repair polymerase. Conducts "gap-filling" DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
• 配列類似性Belongs to the DNA polymerase type-X family.
• ドメインResidues 239-252 form a flexible loop which appears to affect the polymerase fidelity.
• 翻訳後修飾Methylation by PRMT6 stimulates the polymerase activity by enhancing DNA binding and processivity.
• 細胞内局在Nucleus, Cytoplasm

• Target information above from: UniProt accession P06746 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 5423 Human
  • Entrez Gene: 18970 Mouse
  • Entrez Gene: 29240 Rat
  • Omim: 174760 Human
  • SwissProt: P06746 Human
  • SwissProt: Q8K409 Mouse
  • SwissProt: P06766 Rat
  • Unigene: 654484 Human

  • Unigene: 123211 Mouse
  • Unigene: 473777 Mouse
  • Unigene: 9346 Rat

  see all
• 別名
  • DNA directed DNA polymerase beta antibody
  • DNA pol beta antibody
  • DNA polymerase beta antibody

  • DNA polymerase beta subunit antibody
  • DPOLB_HUMAN antibody
  • MGC125976 antibody
  • Pol B antibody
  • Pol beta antibody
  • POLB antibody
  • Polymerase (DNA directed) beta antibody

  see all