製品の概要

  • 製品名Anti-DMGDH antibody
    DMGDH 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to DMGDH
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    antigen sequence, corresponding to C terminal amino acids 776-859 (TLATDDVDPE GNESIWYNGK VVGNTTSGSY SYSIQKSLAF AYVPVQLSEV GQQVEVELLG KNYPAVIIQE PLVLTEPTRN RLQK) of Human DMGDH.

  • ポジティブ・コントロール
    • Human kidney tissue.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab122336 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • パスウェイAmine and polyamine degradation; betaine degradation; sarcosine from betaine: step 2/2.
  • 関連疾患Defects in DMGDH are the cause of DMGDH deficiency (DMGDHD) [MIM:605850]. DMGDHD is a disorder characterized by fish odor, muscle fatigue with increased serum creatine kinase. Biochemically it is characterized by an increase of N,N-dimethylglycine (DMG) in serum and urine.
  • 配列類似性Belongs to the GcvT family.
  • 細胞内局在Mitochondrion.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Dimethylglycine dehydrogenase antibody
    • Dimethylglycine dehydrogenase, mitochondrial antibody
    • Dmgdh antibody
    • M2GD_HUMAN antibody
    • ME2GLYDH antibody
    • mitochondrial antibody
    see all

Anti-DMGDH antibody 画像

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human kidney tissue labelling DMGDH with ab122336. Staining shows strong cytoplasmic positivity in renal tubules.

Anti-DMGDH antibody (ab122336) 使用論文

ab122336 has not yet been referenced specifically in any publications.

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