製品の概要

  • 製品名Anti-DMAP1 antibody [2277C2a]
    DMAP1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [2277C2a] to DMAP1
  • アプリケーション適用あり: WB, Dot blotmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment (N-terminal) DMAP1.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファーPreservative: 0.05% Sodium Azide
    Constituents: 1% BSA, PBS (3.0 mM KCl, 1.5 mM KH PO , 140 mM NaCl, 8.0 mM Na HPO) pH 7.4
  • Concentration information loading...
  • 精製度Protein G purified
  • 特記事項(精製)This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
  • ポリ/モノモノクローナル
  • クローン名2277C2a
  • アイソタイプIgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab50769 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent dilution. Predicted molecular weight: 53 kDa.
Dot blot Use at an assay dependent dilution.

ターゲット情報

  • 関連性DMAP1 is involved in transcription repression and activation. Its interaction with HDAC2 may provide a mechanism for histone deacetylation in heterochromatin following replication of DNA at late firing origins. Can also repress transcription independently of histone deacetylase activity. May specifically potentiate DAXX-mediated repression of glucocorticoid receptor-dependent transcription. Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.
  • 細胞内局在Nuclear
  • 参照データベース
  • 別名
    • DKFZp686L09142 antibody
    • DMAP 1 antibody
    • DNA methyltransferase 1 associated protein 1 antibody
    • DNMAP 1 antibody
    • DNMAP1 antibody
    • DNMT1 associated protein 1 antibody
    • DNMTAP 1 antibody
    • DNMTAP1 antibody
    • EAF 2 antibody
    • EAF2 antibody
    • FLJ11543 antibody
    • KIAA1425 antibody
    • MAT 1 mediated transcriptional repressor antibody
    • MGC55593 antibody
    • SWC 4 antibody
    • SWC4 antibody
    • zgc:55593 antibody
    see all

Anti-DMAP1 antibody [2277C2a] 画像

Anti-DMAP1 antibody [2277C2a] (ab50769) 使用論文

ab50769 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"