製品の概要

  • 製品名Anti-DISP2 antibody
    DISP2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to DISP2
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    N-Terminus of Human DISP2

  • ポジティブ・コントロール
    • Human Small Intestine tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab113837 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 5 µg/ml.

ターゲット情報

  • 関連性DISP2 is the second of three known homologs of the D.melanogaster protein Dispatched. It is a multitransmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored Hedgehog from producing cells. Hedgehog is a major player in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis and the DISP proteins have been implicated in these pathways. Recently, it has been shown that DISP2 is translationally regulated by the microRNA miR-214 in zebrafish. Expression of this miRNA decreased DISP2 promoter activity in vitro and its overexpression in zebrafish resulted in a phenotype identical to that observed by DISP2 mutants. At least two isoforms of DISP2 are known to exist.
  • 細胞内局在Membrane; Multi-pass membrane protein.
  • 参照データベース
  • 別名
    • DISP 2 antibody
    • Dispatched B antibody
    • Dispatched homolog 2 (Drosophila) antibody
    • Dispatched homolog 2 antibody
    • DISPB antibody
    • DKFZp547N223 antibody
    • HsT16908 antibody
    • KIAA1742 antibody
    • Protein dispatched homolog 2 antibody
    see all

Anti-DISP2 antibody 画像

  • ab113837, at 5µg/ml, staining DISP2 in formalin-fixed, paraffin-embedded Human Small Intestine tissue by Immunohistochemistry.

Anti-DISP2 antibody (ab113837) 使用論文

ab113837 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"