製品の概要

  • 製品名Anti-DIS antibody
    DIS 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to DIS
  • アプリケーション適用あり: IP, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Dog, Turkey, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Platypus (Ornithorhynchus anatinus), Elephant
  • 免疫原

    Synthetic peptide (Human) - which represents a portion of Death Inducer with SAP domain encoded within exon 17.

  • ポジティブ・コントロール
    • HeLa cell nuclear extract.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab3743 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP Use a concentration of 1 - 4 µg/ml.
WB 1/2000 - 1/10000. Predicted molecular weight: 140 kDa.

ターゲット情報

  • 機能Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation (By similarity). May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation.
  • 組織特異性Expressed in various epithelial cancer cell lines, including breast, colon, prostate, pancreatic and leukemia. Expression is regulated by growth factors.
  • 配列類似性Contains 1 SAP domain.
  • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Cytoplasm > perinuclear region.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CARP-1 antibody
    • Carp1 antibody
    • Ccar1 antibody
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    • Cell cycle and apoptosis regulatory protein 1 antibody
    • cell division cycle and apoptosis regulator 1 antibody
    • Cell division cycle and apoptosis regulator protein 1 antibody
    • Death inducer with SAP domain antibody
    • FLJ10590 antibody
    • FLJ10839 antibody
    • FLJ13376 antibody
    • FLJ20734 antibody
    • MGC7730 antibody
    • RP11-437A18.1 antibody
    see all

Anti-DIS antibody 画像



  • Predicted band size : 140 kDa


    Sample: Nuclear extract from HeLa cells (50µg)

    Antibody: Affinity purified Rabbit anti-DIS (ab3743) used at 1 / 2000 dilution.

    Detection: ECL.

Anti-DIS antibody (ab3743) 使用論文

ab3743 has not yet been referenced specifically in any publications.

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