製品の概要

  • 製品名Anti-DIRAS1 antibody
    DIRAS1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to DIRAS1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Horse, Chicken, Cow, Cat, Dog, Pig, Zebrafish
  • 免疫原

    Synthetic peptide within residues: CAFMETSAKM NYNVKELFQE LLTLETRRNM SLNIDGKRSG KQKRTDRVKG, corresponding to internal sequence amino acids 144-193 of Human DIRAS1 (NP_660156)

  • ポジティブ・コントロール
    • Jurkat cell lysate.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab90036 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 22 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 関連性The three human RAS genes encode highly related 188 to 189 amino acid proteins, designated H-Ras, N-Ras and K-Ras4A and K-Ras4B (the two K-Ras proteins arise from alternative gene splicing). Ras proteins function as binary molecular switches that control intracellular signaling networks. Ras-regulated signal pathways control such processes as actin cytoskeletal integrity, proliferation, differentiation, cell adhesion, apoptosis, and cell migration. Ras and ras-related proteins are often deregulated in cancers, leading to increased invasion and metastasis, and decreased apoptosis. DIRAS1 displays low GTPase activity and exists predominantly in the GTP-bound form. It is highly expressed in heart and brain.
  • 細胞内局在Cell membrane; Lipid-anchor; Cytoplasmic side
  • 参照データベース
  • 別名
    • Di Ras1 antibody
    • DIRAS family GTP binding RAS like 1 antibody
    • Distinct subgroup of the Ras family member 1 antibody
    • FLJ42681 antibody
    • GBTS1 antibody
    • GTP binding protein Di Ras1 antibody
    • Ras related inhibitor of cell growth antibody
    • RIG antibody
    • Rig protein antibody
    • Small GTP binding tumor suppressor 1 antibody
    see all

Anti-DIRAS1 antibody 画像

  • Anti-DIRAS1 antibody (ab90036) at 1 µg/ml + Jurkat cell lysate at 10 µg

    Secondary
    anti-Rabbit IgG HRP at 1/50000 dilution

    Predicted band size : 22 kDa

Anti-DIRAS1 antibody (ab90036) 使用論文

ab90036 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"