製品の概要

  • 製品名
    Dipyridamole
  • 製品の詳細
    Non-selective phosphodiesterase (PDE) inhibitor
  • 生理活性の詳細
    Non-selective phosphodiesterase (PDE) inhibitor. Exerts antiplatelet, anti-inflammatory, antioxidative and antifibrotic effects. Inhibits hydrolysis of cyclic AMP (cAMP) and cGMP (IC50 = 5 and 3 μM, respectively) in vitro.
  • 精製度
    > 99%

製品の特性

参考文献

This product has been referenced in:
  • Hsieh MS  et al. Dipyridamole suppresses high glucose-induced osteopontin secretion and mRNA expression in rat aortic smooth muscle cells. Circ J 74:1242-50 (2010). Read more (PubMed: 20453393) »
  • Kim HH & Liao JK Translational therapeutics of dipyridamole. Arterioscler Thromb Vasc Biol 28:s39-42 (2008). Read more (PubMed: 18174451) »
  • Souness JE  et al. Pig aortic endothelial-cell cyclic nucleotide phosphodiesterases. Use of phosphodiesterase inhibitors to evaluate their roles in regulating cyclic nucleotide levels in intact cells. Biochem J 266:127-32 (1990). Read more (PubMed: 2155604) »

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