製品の概要

  • 製品名Anti-Dio3 antibody
    Dio3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Dio3
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Rat
    交差が予測される動物種: Human
  • 免疫原

    Synthetic peptide corresponding to a region within internal residues 250-300 of Rat Dio3.

  • ポジティブ・コントロール
    • Rat placenta lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab82041 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.5 µg/ml. Detects a band of approximately 31 kDa (predicted molecular weight: 31 kDa).

ターゲット情報

  • 機能Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during embryological development.
  • 組織特異性Expressed in placenta and several fetal tissues.
  • 配列類似性Belongs to the iodothyronine deiodinase family.
  • 細胞内局在Cell membrane. Endosome membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 5DIII antibody
    • D3 antibody
    • Deiodinase iodothyronine type 3 antibody
    • Deiodinase iodothyronine type III antibody
    • Dio 3 antibody
    • Dio3 antibody
    • DIOIII antibody
    • IOD3_HUMAN antibody
    • Iodothyronine deiodinase placental type antibody
    • MGC124117 antibody
    • MGC124118 antibody
    • Thyroxine deiodinase type III antibody
    • Thyroxine deiodinase type III (selenoprotein) antibody
    • TXDI3 antibody
    • Type 3 DI antibody
    • Type 3 iodothyronine selenodeiodinase antibody
    • Type III 5' deiodinase antibody
    • Type III iodothyronine deiodinase antibody
    • Type-III 5''-deiodinase antibody
    see all

Anti-Dio3 antibody 画像

  • Anti-Dio3 antibody (ab82041) at 0.5 µg/ml + rat placenta lysate

    Predicted band size : 31 kDa
    Observed band size : 31 kDa

Anti-Dio3 antibody (ab82041) 使用論文

This product has been referenced in:
  • Bedolla DE & Torre V A component of retinal light adaptation mediated by the thyroid hormone cascade. PLoS One 6:e26334 (2011). WB ; Rat . Read more (PubMed: 22039463) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"