製品の概要

  • 製品名
    Dihydrokainic acid
  • 製品の詳細
    EAAT2 (GLT-1) inhibitor
  • 別名
    • DHK
  • 生理活性の詳細
    Selective, non-transportable inhibitor of glutamate transporter EAAT2 (GLT-1) (Ki = 23 μM). 130-fold selective over EAAT1 and EAAT3 (Ki > 3 mM).
  • 精製度
    > 99%

製品の特性

参考文献

This product has been referenced in:
  • Fallgren AB & Paulsen RE A microdialysis study in rat brain of dihydrokainate, a glutamate uptake inhibitor. Neurochem Res 21:19-25 (1996). Read more (PubMed: 8833219) »
  • Arriza JL  et al. Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex. J Neurosci 14:5559-69 (1994). Read more (PubMed: 7521911) »
  • Muñoz MD  et al. Effects of dihydrokainic acid on extracellular amino acids and neuronal excitability in the in vivo rat hippocampus. Neuropharmacology 26:1-8 (1987). Read more (PubMed: 2882438) »

See all 9 Publications for this product

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