製品の概要

  • 製品名
    Anti-Digitoxin antibody
  • 製品の詳細
    Rabbit polyclonal to Digitoxin
  • 特異性
    %Cross-Reactivity (determined by RIA): Cortisol <0.5 Digitoxin <3 17-Estradiol <0.5 Progesterone <0.5 Testosterone <0.5
  • アプリケーション
    適用あり: RIAmore details
  • 免疫原

    Digoxin-BSA.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab50318 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
RIA
  • 追加情報
    RIA: 1/10000. Dilute the antiserum in 0.01M phosphate buffered saline, pH 7.4, containing 0.1% sodium azide. RIA Affinity Constant: Ka =3 x 109 - 1 x 1010 L/mole (as determined by a Scatchard plot using RIA).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性
      Digitoxin is a purified cardiac glycoside similar in structure and function to Digoxin. Unlike Digoxin, Digitoxin is eliminated from the body via the liver and not the kidneys. Both drugs are used to treat various heart conditions. Cardiac glycosides bind to a site on the extracellular aspect of the a-subunit of the Na+/K+ ATPase pump in the membranes of heart cells (myocytes). This causes an increase in the level of sodium ions in the myocytes, which then leads to a rise in the level of calcium ions.

    参考文献

    ab50318 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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