製品の概要

  • 製品名Anti-DGAT2L4 antibody
    DGAT2L4 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to DGAT2L4
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Guinea pig, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within C-terminal sequence amino acids 284-333 (GEPLPMPKIE NPSQEIVAKY HTLYIDALRK LFDQHKTKFG ISETQELEII) of human DGAT2L4 (NP_001002254).

  • ポジティブ・コントロール
    • Fetal brain lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab83182 is purified by peptide affinity chromatography method.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab83182 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 38 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay, 1:12500.

ターゲット情報

  • 機能Acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. Has no activity using decyl alcohol and significantly prefers the C16 and C18 alcohols. May also have 2-acylglycerol O-acyltransferase (MGAT) and acyl-CoA:retinol acyltransferase (ARAT) activities, to catalyze the synthesis of diacylglycerols and retinyl esters; however this activity is unclear in vivo.
  • 組織特異性Abundant in tissues rich in sebaceous glands such as the preputial gland and eyelid. Highly expressed in skin, where it is primarily restricted to undifferentiated peripheral sebocytes. Also expressed at lower level in other tissues except pancreas.
  • 配列類似性Belongs to the diacylglycerol acyltransferase family.
  • 細胞内局在Endoplasmic reticulum membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Acyl CoA wax alcohol acyltransferase 2 antibody
    • Acyl-CoA retinol O-fatty-acyltransferase antibody
    • Acyl-CoA wax alcohol acyltransferase 2 antibody
    • ARAT antibody
    • Awat2 antibody
    • AWAT2_HUMAN antibody
    • DC4 antibody
    • Diacylglycerol O acyltransferase 2 like 4 antibody
    • Diacylglycerol O acyltransferase candidate 4 antibody
    • Diacylglycerol O-acyltransferase 2-like protein 4 antibody
    • Diacylglycerol O-acyltransferase candidate 4 antibody
    • hDC4 antibody
    • hWS antibody
    • Long chain alcohol O fatty acyltransferase 2 antibody
    • Long-chain-alcohol O-fatty-acyltransferase 2 antibody
    • MFAT antibody
    • Multifunctional O acyltransferase antibody
    • Multifunctional O-acyltransferase antibody
    • Retinol O-fatty-acyltransferase antibody
    • Wax synthase 2 antibody
    • Wax synthase antibody
    • WS antibody
    see all

Anti-DGAT2L4 antibody 画像

  • Anti-DGAT2L4 antibody (ab83182) at 1 µg/ml (in 5% skim milk / PBS buffer) + fetal brain lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 38 kDa
    Observed band size : 38 kDa

Anti-DGAT2L4 antibody (ab83182) 使用論文

This product has been referenced in:
  • Kaylor JJ  et al. Identification of the 11-cis-specific retinyl-ester synthase in retinal Müller cells as multifunctional O-acyltransferase (MFAT). Proc Natl Acad Sci U S A 111:7302-7 (2014). Read more (PubMed: 24799687) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"