製品の概要

  • 製品名Dexmedetomidine hydrochloride
  • 製品の詳細
    Potent, highly selective α2 agonist
  • 生理活性の詳細Potent, highly selective α2 agonist. (Ki values are 1.08 and 1750 nM at α2 and α1 receptors, respectively). Active enantiomer of medetomidine (ab120787). Displays numerous actions including sedative, analgesic, anxiolytic, and antiulcerative properties.
  • 精製度> 99%

製品の特性

  • 体系名4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride
  • 分子量236.74
  • 構造式Chemical Structure
  • 分子式C13H16N2.HCl
  • CAS 番号145108-58-3
  • 保存方法Store at Room Temperature. The product can be stored for up to 12 months.
  • 溶解性Soluble in water to 100 mM
  • 使用に関する注意

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • 由来

    Synthetic

  • 研究分野

    Dexmedetomidine hydrochloride (ab120767) 使用論文

    This product has been referenced in:
    • Polat B  et al. Antiulcerative effect of dexmedetomidine on indomethacin-induced gastric ulcer in rats. Pharmacol Rep 63:518-26 (2011). Read more (PubMed: 21602607) »
    • Fisher B  et al. Antinociceptive properties of intrathecal dexmedetomidine in rats. Eur J Pharmacol 192:221-5 (1991). Read more (PubMed: 1674472) »
    • Virtanen R  et al. Characterization of the selectivity, specificity and potency of medetomidine as an alpha 2-adrenoceptor agonist. Eur J Pharmacol 150:9-14 (1988). Read more (PubMed: 2900154) »

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"