Anti-Desmoglein 2 抗体 (ab96761)

製品の概要

  • 製品名Anti-Desmoglein 2 antibody
    Desmoglein 2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Desmoglein 2
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    Recombinant protein fragment corresponding to a region within amino acids 1 and 176 of Desmoglein 2 (NP_001934).

  • ポジティブ・コントロール
    • WB: 293T, H1299 and MOLT4 whole cell lysates; HepG2 cell lysate IHC-P: DU145 xenograft

法規制情報

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab96761 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 122 kDa.
IHC-P 1/100 - 1/500.

ターゲット情報

  • 機能Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
  • 組織特異性All of the tissues tested and carcinomas.
  • 関連疾患Defects in DSG2 are the cause of familial arrhythmogenic right ventricular dysplasia type 10 (ARVD10) [MIM:610193]; also known as arrhythmogenic right ventricular cardiomyopathy 10 (ARVC10). ARVD is an autosomal dominant disease characterized by partial degeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall.
    Genetic variations in DSG2 are the cause of susceptibility to cardiomyopathy dilated type 1BB (CMD1BB) [MIM:612877]. A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
  • 配列類似性Contains 4 cadherin domains.
  • ドメインCalcium may be bound by the cadherin-like repeats.
  • 細胞内局在Cell membrane. Cell junction > desmosome.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ARVC 10 antibody
    • ARVC10 antibody
    • ARVD 10 antibody
    • ARVD10 antibody
    • Cadherin family member 5 antibody
    • CDHF 5 antibody
    • CDHF5 antibody
    • CMD1BB antibody
    • Desmoglein 2 antibody
    • Desmoglein-2 antibody
    • Desmoglein2 antibody
    • DSG 2 antibody
    • DSG2 antibody
    • DSG2_HUMAN antibody
    • HDGC antibody
    • HDGC included antibody
    • Human Desmoglein colon antibody
    • MGC117034 antibody
    • MGC117036 antibody
    • MGC117037 antibody
    see all

Anti-Desmoglein 2 antibody 画像

  • All lanes : Anti-Desmoglein 2 antibody (ab96761) at 1/1000 dilution

    Lane 1 : 293T whole cell lysate
    Lane 2 : H1299 whole cell lysate
    Lane 3 : MOLT4 whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 122 kDa
  • Immunohistochemical analysis of Desmoglein 2 in paraffin embedded DU145 xenograft, using ab96761 at a 1/100 dilution.

Anti-Desmoglein 2 antibody (ab96761) 使用論文

ab96761 has not yet been referenced specifically in any publications.

Product Wall

Vielen Dank für Ihre Geduld. Ich kann Ihnen jetzt auch bestätigen, dass der ab14415 ein Epitop auf dem extrazellulären Part des Desmoglein 2 erkennt. Auch der ab96761 erkennt das extrazelluläre Desmoglein 2, da der Antikörper gegen ein rekombina...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"