製品の概要

  • 製品名
    Anti-Desmoglein 1 antibody
    Desmoglein 1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Desmoglein 1
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 470-499 of Human Desmoglein 1 (NP_001933.2, Q02413).

  • ポジティブ・コントロール
    • K562 cell line lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab123414 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 114 kDa.

ターゲット情報

  • 機能
    Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
  • 組織特異性
    Epidermis, tongue, tonsil and esophagus.
  • 関連疾患
    Defects in DSG1 are the cause of palmoplantar keratoderma striate type 1 (SPPK1) [MIM:148700]; also known as keratosis palmoplantaris striata I. SPPK1 is a dermatoligical disorder characterized by thickening of the skin on the palms and soles, and longitudinal hyperkeratotic lesions on the palms, running the length of each finger.
  • 配列類似性
    Contains 4 cadherin domains.
  • ドメイン
    Calcium may be bound by the cadherin-like repeats.
  • 細胞内局在
    Cell membrane. Cell junction > desmosome.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Cadherin family member 4 antibody
    • CDHF4 antibody
    • Desmoglein-1 antibody
    • Desmosomal glycoprotein 1 antibody
    • DG1 antibody
    • DGI antibody
    • DSG antibody
    • DSG1 antibody
    • DSG1_HUMAN antibody
    • EPKHE antibody
    • EPKHIA antibody
    • Pemphigus foliaceus antigen antibody
    • PPKS1 antibody
    • SPPK1 antibody
    see all

画像

  • Anti-Desmoglein 1 antibody (ab123414) at 1/100 dilution + K562 cell line lysate at 35 µg

    Predicted band size : 114 kDa

プロトコール

参考文献

ab123414 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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