製品の概要

  • 製品名Anti-Desmoglein 1 antibody [3G131]
    Desmoglein 1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [3G131] to Desmoglein 1
  • 特異性This antibody does not cross-react with Desmoglein 2 or Desmoglein 3.
  • アプリケーション適用あり: WB, IPmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Intracellular domain of Desmoglein 1 (Human).

  • ポジティブ・コントロール
    • Differentiated keratinocytes and Desmoglein 1 transfected cells.
  • 特記事項For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab14414 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 114 kDa.
IP Use a concentration of 5 - 10 µg/ml.

ターゲット情報

  • 機能Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
  • 組織特異性Epidermis, tongue, tonsil and esophagus.
  • 関連疾患Defects in DSG1 are the cause of palmoplantar keratoderma striate type 1 (SPPK1) [MIM:148700]; also known as keratosis palmoplantaris striata I. SPPK1 is a dermatoligical disorder characterized by thickening of the skin on the palms and soles, and longitudinal hyperkeratotic lesions on the palms, running the length of each finger.
  • 配列類似性Contains 4 cadherin domains.
  • ドメインCalcium may be bound by the cadherin-like repeats.
  • 細胞内局在Cell membrane. Cell junction > desmosome.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Cadherin family member 4 antibody
    • CDHF4 antibody
    • Desmoglein-1 antibody
    • Desmosomal glycoprotein 1 antibody
    • DG1 antibody
    • DGI antibody
    • DSG antibody
    • DSG1 antibody
    • DSG1_HUMAN antibody
    • EPKHE antibody
    • EPKHIA antibody
    • Pemphigus foliaceus antigen antibody
    • PPKS1 antibody
    • SPPK1 antibody
    see all

Anti-Desmoglein 1 antibody [3G131] (ab14414) 使用論文

ab14414 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab14414.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"