製品の概要

  • 製品名Anti-Desmocollin 2 + 3 antibody [3G130]
  • 製品の詳細
    Mouse monoclonal [3G130] to Desmocollin 2 + 3
  • 特異性ab69406 reacts with Desmocollin 2 and Desmocollin 3 human proteins, with a particularly strong reaction to Desmocollin 2. Crossreactivity with other desmocollin family members has not been observed.
  • アプリケーション適用あり: WB, IP, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Human Desmocollin 2 extracellular domain

  • ポジティブ・コントロール
    • A431 Cells, Non-Stimulated in RIPA Buffer, Sample Buffer.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノモノクローナル
  • クローン名3G130
  • アイソタイプIgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab69406 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
IP
ICC/IF
  • 追加情報ICC/IF: Use at a concentration of 20 - 50 µg/ml.
    IP: Use at a concentration of 5 - 10 µg/ml.
    WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 120 kDa, corresponding to Desmocollin 2, and a band of approximately 105 kDa, corresponding to Desmocollin 3 (predicted molecular weight: 100 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性Members of the desmocollin subfamily are calcium-dependent glycoproteins. They are part of the cadherin superfamily. These desmosomal family members, together with the desmogleins, are mainly found in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction. They are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650kb combined.
    • 細胞内局在Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.
    • 参照データベース
    • 別名
      • ARVD11 antibody
      • CDHF2 antibody
      • CDHF3 antibody
      • Desmocollin 2 antibody
      • Desmocollin 3 antibody
      • Desmosomal glycoprotein II and III antibody
      • DG2 antibody
      • DGII/III antibody
      • DSC antibody
      • DSC1 antibody
      • DSC2 antibody
      • DSC3 antibody
      • DSC4 antibody
      see all

    Anti-Desmocollin 2 + 3 antibody [3G130] (ab69406) 使用論文

    This product has been referenced in:
    • Shapiro JP  et al. A quantitative proteomic workflow for characterization of frozen clinical biopsies: Laser capture microdissection coupled with label-free mass spectrometry. J Proteomics : (2012). IHC . Read more (PubMed: 23022584) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab69406.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"