製品の概要

  • 製品名
    Anti-Dermatopontin antibody
    Dermatopontin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Dermatopontin
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 52-80 of Human Dermatopontin (NP_001928.2).

  • ポジティブ・コントロール
    • Dermatopontin-transfected 293 cell line lysate.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • バッファー
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 精製度
    Ammonium Sulphate Precipitation
  • 特記事項(精製)
    ab112600 is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab112600 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/50 - 1/100. Predicted molecular weight: 24 kDa.

ターゲット情報

  • 機能
    Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. Enhances TGFB1 activity. Inhibits cell proliferation. Accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation.
  • 組織特異性
    Expressed in fibroblasts, heart, skeletal muscle, brain and pancreas. Expressed at an intermediate level in lung and kidney, and at a low level in liver and placenta. Expressed at a lower level in fibroblasts from hypertrophic scar lesional skin and in fibroblasts from patients with systemic sclerosis than in normal skin fibroblasts.
  • 配列類似性
    Belongs to the dermatopontin family.
  • 翻訳後修飾
    Sulfated on tyrosine residue(s).
  • 細胞内局在
    Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • 参照データベース
  • 別名
    • DERM_HUMAN antibody
    • Dermatopontin antibody
    • Dpt antibody
    • TRAMP antibody
    • Tyrosine rich acidic matrix protein antibody
    • Tyrosine-rich acidic matrix protein antibody
    see all

画像

  • All lanes : Anti-Dermatopontin antibody (ab112600) at 1/50 dilution

    Lane 1 : 293 cell line lysates
    Lane 2 : 293 cell line lysates, transiently transfected with the Dermatopontin gene

    Lysates/proteins at 2 µg per lane.


    Predicted band size : 24 kDa

プロトコール

参考文献

ab112600 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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