製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to DERL3
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Goat, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within internal amino acids 71-120 (

    FFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL

    ) of Human DERL3 (NP_001002862).

  • ポジティブ・コントロール
    • THP1 cell lysate

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab99107 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 27 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate.
  • 組織特異性
    Unlike DERL1 and DERL2, restricted to several tissues. Expressed at high levels in placenta, pancreas, spleen and small intestine.
  • 配列類似性
    Belongs to the derlin family.
  • 細胞内局在
    Endoplasmic reticulum membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C22orf14 antibody
    • Degradation in endoplasmic reticulum protein 3 antibody
    • DER 3 antibody
    • Der1 like domain family member 3 antibody
    • Der1 like protein 3 antibody
    • Der1-like protein 3 antibody
    • DER3 antibody
    • DERL 3 antibody
    • Derl3 antibody
    • DERL3_HUMAN antibody
    • Derlin 3 antibody
    • Derlin 3 protein antibody
    • Derlin-3 antibody
    • Derlin3 antibody
    • DERtrin 3 antibody
    • DERtrin-3 antibody
    • DERtrin3 antibody
    • IZP 6 antibody
    • IZP6 antibody
    • LLN 2 antibody
    • LLN2 antibody
    • MGC71803 antibody
    see all

画像

  • Anti-DERL3 antibody (ab99107) at 1 µg/ml + THP1 Cell Lysate at 10 µg

    Predicted band size : 27 kDa

プロトコール

参考文献

ab99107 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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