製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to DERL3
  • アプリケーション
    適用あり: WB, IP, ICC/IFmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rat, Cow
  • 免疫原

    Synthetic peptide:

    QPGGKRLLQTPGFL

    conjugated to KLH, corresponding to amino acids 192-205 of Human DERL3

  • ポジティブ・コントロール
    • Whole extract of HEK-293T cells expressing recombinant human DERL3 and human HeLa cells.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: 15mM Sodium Azide
    Constituents: 0.01M PBS, pH 7.4
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab69812 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
IP
ICC/IF
  • 追加情報
    ICC/IF: Use at a concentration of 10 - 20 µg/ml.
    IP: Use at a concentration of 5 - 10 µg.
    WB: Use at a concentration of 2 - 5 µg/ml. Predicted molecular weight: 27 kDa.
    Detection of the band by immunoblotting is specifically inhibited by the immunizing peptide.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate.
    • 組織特異性
      Unlike DERL1 and DERL2, restricted to several tissues. Expressed at high levels in placenta, pancreas, spleen and small intestine.
    • 配列類似性
      Belongs to the derlin family.
    • 細胞内局在
      Endoplasmic reticulum membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • C22orf14 antibody
      • Degradation in endoplasmic reticulum protein 3 antibody
      • DER 3 antibody
      • Der1 like domain family member 3 antibody
      • Der1 like protein 3 antibody
      • Der1-like protein 3 antibody
      • DER3 antibody
      • DERL 3 antibody
      • Derl3 antibody
      • DERL3_HUMAN antibody
      • Derlin 3 antibody
      • Derlin 3 protein antibody
      • Derlin-3 antibody
      • Derlin3 antibody
      • DERtrin 3 antibody
      • DERtrin-3 antibody
      • DERtrin3 antibody
      • IZP 6 antibody
      • IZP6 antibody
      • LLN 2 antibody
      • LLN2 antibody
      • MGC71803 antibody
      see all

    参考文献

    ab69812 has not yet been referenced specifically in any publications.

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    There are currently no Customer reviews or Questions for ab69812.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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