製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to DERL2
  • 特異性
    This antibody reacts specifically with human 27 kDa DERL2 protein.
  • アプリケーション
    適用あり: IHC-P, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide derived from the C-terminal domain of (Human) DERL2 protein.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    Preservative: None
    Constituents: Whole serum
  • 精製度
    Whole antiserum
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab71552 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use at an assay dependent concentration.
WB 1/200 - 1/2000. Predicted molecular weight: 27 kDa.

ターゲット情報

  • 機能
    Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins. May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In contrast to DERL1, it is not involved in the degradation of MHC class I heavy chains following infection by cytomegaloviruses. May play a role in cell proliferation.
  • 組織特異性
    Ubiquitous. Overexpressed in various hepatocarcinomas.
  • 配列類似性
    Belongs to the derlin family.
  • 細胞内局在
    Endoplasmic reticulum membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Carcinoma related antibody
    • CGI 101 antibody
    • Degradation in endoplasmic reticulum protein 2 antibody
    • DER 2 antibody
    • Der1 like domain family member 2 antibody
    • Der1-like protein 2 antibody
    • DER2 antibody
    • DERL 2 antibody
    • DERL2 antibody
    • DERL2_HUMAN antibody
    • Derlin 2 antibody
    • Derlin-2 antibody
    • Derlin2 antibody
    • DERtrin 2 antibody
    • DERtrin-2 antibody
    • DERtrin2 antibody
    • F LAN 1 antibody
    • F LANa antibody
    • F-LAN-1 antibody
    • F-LANa antibody
    • FLANa antibody
    see all

Anti-DERL2 antibody (ab71552) 使用論文

ab71552 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab71552.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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