The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 77 kDa.
機能Part of the CASK/TRB1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.
組織特異性Ubiquitously expressed, with highest levels in brain, testis and heart, and lowest levels in liver and pancreas.
配列類似性Belongs to the nucleosome assembly protein (NAP) family.
翻訳後修飾Phosphorylation at Ser-20 and/or Thr-340 impairs function on cell proliferation.
細胞内局在Nucleus. Cytoplasm. Enriched in transcriptionally active regions of chromatin in neurons.