製品の概要

  • 製品名Demethoxycurcumin
  • 製品の詳細
    Natural demethoxy curcuminoid. Anticancer, antiproliferative and antioxidant activity.
  • 生理活性の詳細Natural demethoxy curcuminoid. Anticancer, antiproliferative and antioxidant activity. Inhibits various signaling pathways including Wnt/β-catenin, AMPK and MAPK.
  • 精製度> 98%

製品の特性

  • 体系名(1E,6E)-1-(4-Hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione
  • 分子量338.36
  • 構造式Chemical Structure
  • 分子式C20H18O5
  • CAS 番号22608-11-3
  • PubChem 登録番号5469424
  • 保存方法Store at -20°C. Store at -20°C long term. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under Desiccating conditions.
  • 溶解性Soluble in DMSO to 100 mM and ethanol to 25 mM
  • 使用に関する注意

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES 線形表記Oc1ccc(cc1OC)/C=C/C(=O)CC(=O)/C=C/c2ccc(O)cc2
  • 由来

    Curcuma longa

  • 研究分野

    Demethoxycurcumin (ab120987) 使用論文

    This product has been referenced in:
    • Ni X  et al. Demethoxycurcumin inhibits cell proliferation, migration and invasion in prostate cancer cells. Oncol Rep 28:85-90 (2012). Read more (PubMed: 22552297) »
    • Purkayastha S  et al. Curcumin Blocks Brain Tumor Formation. Brain Res : (2009). Read more (PubMed: 19368804) »
    • Ryu MJ  et al. Natural derivatives of curcumin attenuate the Wnt/beta-catenin pathway through down-regulation of the transcriptional coactivator p300. Biochem Biophys Res Commun 377:1304-8 (2008). Read more (PubMed: 19000900) »

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"