製品の概要

  • 製品名Anti-Dematin antibody
    Dematin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Dematin
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Horse, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 142-191 (KKPPIYKQRE SVGGSPQTKH LIEDLIIESS KFPAAQPPDP NQPAKIETDY) of Human Dematin (NP_001969).

  • ポジティブ・コントロール
    • Jurkat cell lysate.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab116391 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 46 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Actin-bundling protein. May function in mitogen-activated protein kinase pathway.
  • 組織特異性Heart, brain, lung, skeletal muscle, and kidney.
  • 配列類似性Belongs to the villin/gelsolin family.
    Contains 1 HP (headpiece) domain.
  • ドメインContains at least two actin-binding sites, one in the headpiece domain and one in the amino-terminal portion.
    Consists of a large core fragment, the amino-terminal portion, and a small headpiece, the C-terminal portion. The headpiece can bind but cannot bundle actin filaments.
  • 翻訳後修飾Actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase.
    The N-terminus is blocked.
  • 細胞内局在Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • DEMA antibody
    • DEMA_HUMAN antibody
    • Dematin antibody
    • DMT antibody
    • EPB49 antibody
    • erythrocyte membrane protein band 4.9 (dematin) antibody
    • Erythrocyte membrane protein band 4.9 antibody
    see all

Anti-Dematin antibody 画像

  • Anti-Dematin antibody (ab116391) at 1 µg/ml + Jurkat cell lysate at 10 µg

    Predicted band size : 46 kDa

Anti-Dematin antibody (ab116391) 使用論文

ab116391 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"