Anti-delta 1 Catenin/CAS (phospho Y291) 抗体 [EP2385Y] (ab81274)
Key features and details
- Rabbit monoclonal [EP2385Y] to delta 1 Catenin/CAS (phospho Y291)
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Related conjugates and formulations
製品の概要
-
製品名
Anti-delta 1 Catenin/CAS (phospho Y291) antibody [EP2385Y]
delta 1 Catenin/CAS 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EP2385Y] to delta 1 Catenin/CAS (phospho Y291) -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details
適用なし: Flow Cyt,ICC/IF,IHC-P or IP -
種交差性
交差種: Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
-
ポジティブ・コントロール
- Jurkat cell lysate treated with pervanadate
-
特記事項
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading...
-
精製度
Tissue culture supernatant -
ポリ/モノ
モノクローナル -
クローン名
EP2385Y -
アイソタイプ
IgG -
研究分野
関連製品
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab81274の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
1/10000 - 1/20000. Predicted molecular weight: 108 kDa.
|
特記事項 |
---|
WB
1/10000 - 1/20000. Predicted molecular weight: 108 kDa. |
ターゲット情報
-
機能
Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage. -
組織特異性
Expressed in vascular endothelium. -
配列類似性
Belongs to the beta-catenin family.
Contains 10 ARM repeats. -
ドメイン
A possible nuclear localization signal exists in all isoforms where Asp-626--631-Arg are deleted. -
翻訳後修飾
Phosphorylated by protein-tyrosine kinases. Dephosphorylated by PTPRJ. -
細胞内局在
Cytoplasm. Nucleus. Cell membrane. Interaction with GLIS2 promotes nuclear translocation (By similarity). NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm. - Information by UniProt
-
参照データベース
- Entrez Gene: 1500 Human
- Omim: 601045 Human
- SwissProt: O60716 Human
- Unigene: 166011 Human
-
別名
- Cadherin associated Src substrate antibody
- Cadherin-associated Src substrate antibody
- CAS antibody
see all
画像
-
All lanes : Anti-delta 1 Catenin/CAS (phospho Y291) antibody [EP2385Y] (ab81274) at 1/20000 dilution
Lane 1 : Jurkat cell lysate untreated
Lane 2 : Jurkat cell lysate treated with pervanadate
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : HRP labelled goat anti rabbit at 1/2000 dilution
Predicted band size: 108 kDa
Observed band size: 108 kDa
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (0)
ab81274 は論文での使用が確認できていません。