Anti-delta 1 Catenin (phospho Y228) 抗体 [E205] (ab32403)

製品の概要

  • 製品名Anti-delta 1 Catenin (phospho Y228) antibody [E205]
    delta 1 Catenin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [E205] to delta 1 Catenin (phospho Y228)
  • 特異性This antibody only detects delta 1 Catenin phosphorylated on Tyrosine 228.
  • アプリケーション適用あり: WB, IHC-P, ICC, IPmore details
    適用なし: Flow Cyt
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    A synthetic phospho peptide corresponding to residues surrounding Tyr 228 of human delta 1 Catenin.

  • ポジティブ・コントロール
    • WB: HeLa cell lysate. IHC-P: Breast carcinoma.
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab32403 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/5000 - 1/20000. Detects a band of approximately 115 kDa (predicted molecular weight: 108 kDa).
IHC-P 1/50.
ICC 1/100.
IP 1/100.
  • 追加情報Is unsuitable for Flow Cyt.
  • ターゲット情報

    • 機能Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
    • 組織特異性Expressed in vascular endothelium.
    • 配列類似性Belongs to the beta-catenin family.
      Contains 10 ARM repeats.
    • ドメインA possible nuclear localization signal exists in all isoforms where Asp-626--631-Arg are deleted.
    • 翻訳後修飾Phosphorylated by protein-tyrosine kinases. Dephosphorylated by PTPRJ.
    • 細胞内局在Cytoplasm. Nucleus. Cell membrane. Interaction with GLIS2 promotes nuclear translocation (By similarity). NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Cadherin associated Src substrate antibody
      • Cadherin-associated Src substrate antibody
      • CAS antibody
      • Catenin (cadherin associated protein) delta 1 antibody
      • Catenin delta 1 antibody
      • Catenin delta antibody
      • Catenin delta-1 antibody
      • CTND1_HUMAN antibody
      • CTNND 1 antibody
      • CTNND antibody
      • CTNND1 antibody
      • KIAA0384 antibody
      • p120 antibody
      • P120 CAS antibody
      • p120 catenin antibody
      • P120 CTN antibody
      • p120(cas) antibody
      • p120(ctn) antibody
      • P120CAS antibody
      • P120CTN antibody
      see all

    Anti-delta 1 Catenin (phospho Y228) antibody [E205] 画像

    • All lanes : Anti-delta 1 Catenin (phospho Y228) antibody [E205] (ab32403)

      Lane 1 : HeLa cell lysate, untreated.
      Lane 2 : HeLa cell lysate, treated with Pervanandate.
      Lane 3 : HeLa cell lysate, treated with Phosphatase.


      Predicted band size : 108 kDa
      Observed band size : 115 kDa (why is the actual band size different from the predicted?)
    • Ab32403, at a 1/50 dilution, staining delta 1 Catenin in paraffin embedded breast carcinoma tissue sections by Immunohistochemistry.

    Anti-delta 1 Catenin (phospho Y228) antibody [E205] (ab32403) 使用論文

    This product has been referenced in:
    • Ma LW  et al. Phosphorylated p120-catenin expression has predictive value for oral cancer progression. J Clin Pathol 65:315-9 (2012). Read more (PubMed: 22259181) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"