Anti-delta 1 Catenin (phospho Y228) 抗体 (ab61026)

製品の概要

  • 製品名Anti-delta 1 Catenin (phospho Y228) antibody
    delta 1 Catenin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to delta 1 Catenin (phospho Y228)
  • 特異性Detects endogenous levels of delta 1 Catenin only when phosphorylated at tyrosine 228
  • アプリケーション適用あり: WB, IHC-P, ICC/IF, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic phosphopeptide from around the phosphorylation site of tyrosine 228 (DNYPGS) of human delta 1 Catenin

  • ポジティブ・コントロール
    • HUVEC cells Human brain tissue

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)Affinity purified from rabbit antiserum by affinity chromatography using epitope specific phosphopeptide. The antibody against non phosphopeptide was removed by chromatography using non phosphopeptide corresponding to the phosphorylation site.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab61026 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 108 kDa (predicted molecular weight: 108 kDa).
IHC-P 1/50 - 1/100.
ICC/IF 1/500 - 1/1000.
ELISA 1/10000.

ターゲット情報

  • 機能Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
  • 組織特異性Expressed in vascular endothelium.
  • 配列類似性Belongs to the beta-catenin family.
    Contains 10 ARM repeats.
  • ドメインA possible nuclear localization signal exists in all isoforms where Asp-626--631-Arg are deleted.
  • 翻訳後修飾Phosphorylated by protein-tyrosine kinases. Dephosphorylated by PTPRJ.
  • 細胞内局在Cytoplasm. Nucleus. Cell membrane. Interaction with GLIS2 promotes nuclear translocation (By similarity). NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Cadherin associated Src substrate antibody
    • Cadherin-associated Src substrate antibody
    • CAS antibody
    • Catenin (cadherin associated protein) delta 1 antibody
    • Catenin delta 1 antibody
    • Catenin delta antibody
    • Catenin delta-1 antibody
    • CTND1_HUMAN antibody
    • CTNND 1 antibody
    • CTNND antibody
    • CTNND1 antibody
    • KIAA0384 antibody
    • p120 antibody
    • P120 CAS antibody
    • p120 catenin antibody
    • P120 CTN antibody
    • p120(cas) antibody
    • p120(ctn) antibody
    • P120CAS antibody
    • P120CTN antibody
    see all

Anti-delta 1 Catenin (phospho Y228) antibody 画像

  • Immunohistochemical analysis of paraffin embedded human brain tissue using ab61026 at 1/50 dilution. Samples were treated -/+ immunising peptide.
  • All lanes : Anti-delta 1 Catenin (phospho Y228) antibody (ab61026) at 1/500 dilution

    Lane 1 : HUVEC extract
    Lane 2 : HUVEC extract with immunising peptide


    Predicted band size : 108 kDa
    Observed band size : 108 kDa
  • Immunofluorescence analysis of HUVECs labelled with ab61026 at 1/500 dilution. Left: untreated sample. Right: sample treated with immunising peptide.

Anti-delta 1 Catenin (phospho Y228) antibody (ab61026) 使用論文

ab61026 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"