Anti-delta 1 Catenin (phospho T916) 抗体 [EPR2383] (ab79400)

製品の概要

• 製品名
  Anti-delta 1 Catenin (phospho T916) antibody [EPR2383]
  delta 1 Catenin 一次抗体 製品一覧
• 製品の詳細
  Rabbit monoclonal [EPR2383] to delta 1 Catenin (phospho T916)
• 特異性
  ab79400 only detects delta 1 Catenin phosphorylated on threonine 916.
• アプリケーション
  適用あり: WB, IHC-P, ICCmore details
  適用なし: Flow Cyt or IP
• 種交差性
  交差種: Human
  
• 免疫原

  A phospho-specific peptide corresponding to residues surrounding threonine 916 of human delta 1 Catenin

• ポジティブ･コントロール
  • 293T cell lysates treated with calyculin A; human ovarian carcinoma tissue.
• 特記事項

  This product is a recombinant rabbit monoclonal antibody.

  Produced using Abcam’s RabMAb^® technology. RabMAb^® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

  Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

製品の特性

• 製品の状態
  Liquid
• 保存方法
  Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
• バッファー
  PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
• 精製度
  Tissue culture supernatant
• ポリ/モノ
  モノクローナル
• クローン名
  EPR2383
• アイソタイプ
  IgG
• 研究分野
  • Signal Transduction
  • Cytoskeleton / ECM
  • Cytoskeleton
  • Microfilaments
  • Actin etc
  • Catenins

  • Stem Cells
  • Signaling Pathways
  • Wnt
  • Cytoplasmic

アプリケーション

ターゲット情報

• 機能
  Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
• 組織特異性
  Expressed in vascular endothelium.
• 配列類似性
  Belongs to the beta-catenin family.
  Contains 10 ARM repeats.
• ドメイン
  A possible nuclear localization signal exists in all isoforms where Asp-626--631-Arg are deleted.
• 翻訳後修飾
  Phosphorylated by protein-tyrosine kinases. Dephosphorylated by PTPRJ.
• 細胞内局在
  Cytoplasm. Nucleus. Cell membrane. Interaction with GLIS2 promotes nuclear translocation (By similarity). NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm.

• Target information above from: UniProt accession O60716 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 1500 Human
  • Omim: 601045 Human
  • SwissProt: O60716 Human
  • Unigene: 166011 Human
• 別名
  • Cadherin associated Src substrate antibody
  • Cadherin-associated Src substrate antibody
  • CAS antibody

  • Catenin (cadherin associated protein) delta 1 antibody
  • Catenin delta 1 antibody
  • Catenin delta antibody
  • Catenin delta-1 antibody
  • CTND1_HUMAN antibody
  • CTNND 1 antibody
  • CTNND antibody
  • CTNND1 antibody
  • KIAA0384 antibody
  • p120 antibody
  • P120 CAS antibody
  • p120 catenin antibody
  • P120 CTN antibody
  • p120(cas) antibody
  • p120(ctn) antibody
  • P120CAS antibody
  • P120CTN antibody

  see all

プロトコール

• Western blot protocols
• Immunohistochemistry protocols
• Immunocytochemistry & immunofluorescence protocols