製品の概要

  • 製品名Anti-delta 1 Catenin antibody
    delta 1 Catenin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to delta 1 Catenin
  • アプリケーション適用あり: WB, ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthesized non phosphopeptide derived from human delta 1 Catenin around the phosphorylation site of tyrosine 228 (D-N-YP-G-S).

  • ポジティブ・コントロール
    • Extracts from HuvEc cells, human brain tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab74124 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 108 kDa (predicted molecular weight: 108 kDa).
ELISA 1/5000.
IHC-P 1/50 - 1/100.

ターゲット情報

  • 機能Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
  • 組織特異性Expressed in vascular endothelium.
  • 配列類似性Belongs to the beta-catenin family.
    Contains 10 ARM repeats.
  • ドメインA possible nuclear localization signal exists in all isoforms where Asp-626--631-Arg are deleted.
  • 翻訳後修飾Phosphorylated by protein-tyrosine kinases. Dephosphorylated by PTPRJ.
  • 細胞内局在Cytoplasm. Nucleus. Cell membrane. Interaction with GLIS2 promotes nuclear translocation (By similarity). NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Cadherin associated Src substrate antibody
    • Cadherin-associated Src substrate antibody
    • CAS antibody
    • Catenin (cadherin associated protein) delta 1 antibody
    • Catenin delta 1 antibody
    • Catenin delta antibody
    • Catenin delta-1 antibody
    • CTND1_HUMAN antibody
    • CTNND 1 antibody
    • CTNND antibody
    • CTNND1 antibody
    • KIAA0384 antibody
    • p120 antibody
    • P120 CAS antibody
    • p120 catenin antibody
    • P120 CTN antibody
    • p120(cas) antibody
    • p120(ctn) antibody
    • P120CAS antibody
    • P120CTN antibody
    see all

Anti-delta 1 Catenin antibody 画像

  • All lanes : Anti-delta 1 Catenin antibody (ab74124) at 1/500 dilution

    Lane 1 : Extracts from HuvEc cells
    Lane 2 : Extracts from HuvEc cells, plus immunising peptide at 5 µg

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 108 kDa
    Observed band size : 108 kDa
  • ab74124, at a 1/50 dilution, staining delta 1 Catenin in paraffin embedded human brain tissue by Immunohistochemistry, in the absence (left image) or presence (right image) of the immunising peptide.

Anti-delta 1 Catenin antibody (ab74124) 使用論文

ab74124 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"