製品の概要

  • 製品名Anti-delta 1 Catenin antibody
    delta 1 Catenin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to delta 1 Catenin
  • アプリケーション適用あり: WB, IPmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat, Rabbit, Horse, Guinea pig, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Platypus (Ornithorhynchus anatinus), Elephant
  • 免疫原

    Synthetic peptide corresponding to a region between residues 75 and 125 of human delta 1 Catenin (NP_001322.1).

  • ポジティブ・コントロール
    • HeLa, 293T and NIH3T3 whole cell lysates.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab72039 was affinity purified using an epitope specific to delta 1 Catenin immobilized on solid support.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab72039 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/2000 - 1/10000. Detects a band of approximately 117 kDa (predicted molecular weight: 108 kDa).
IP Use at 2-5 µg/mg of lysate.

ターゲット情報

  • 機能Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
  • 組織特異性Expressed in vascular endothelium.
  • 配列類似性Belongs to the beta-catenin family.
    Contains 10 ARM repeats.
  • ドメインA possible nuclear localization signal exists in all isoforms where Asp-626--631-Arg are deleted.
  • 翻訳後修飾Phosphorylated by protein-tyrosine kinases. Dephosphorylated by PTPRJ.
  • 細胞内局在Cytoplasm. Nucleus. Cell membrane. Interaction with GLIS2 promotes nuclear translocation (By similarity). NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Cadherin associated Src substrate antibody
    • Cadherin-associated Src substrate antibody
    • CAS antibody
    • Catenin (cadherin associated protein) delta 1 antibody
    • Catenin delta 1 antibody
    • Catenin delta antibody
    • Catenin delta-1 antibody
    • CTND1_HUMAN antibody
    • CTNND 1 antibody
    • CTNND antibody
    • CTNND1 antibody
    • KIAA0384 antibody
    • p120 antibody
    • P120 CAS antibody
    • p120 catenin antibody
    • P120 CTN antibody
    • p120(cas) antibody
    • p120(ctn) antibody
    • P120CAS antibody
    • P120CTN antibody
    see all

Anti-delta 1 Catenin antibody 画像

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human ovarian carcinoma tissue labelling delta 1 Catenin with ab72039 at 1/1000 (0.2µg/ml). Detection: DAB.
  • All lanes : Anti-delta 1 Catenin antibody (ab72039) at 0.04 µg/ml

    Lane 1 : HeLa whole cell lysate at 50 µg
    Lane 2 : HeLa whole cell lysate at 15 µg
    Lane 3 : HeLa whole cell lysate at 5 µg
    Lane 4 : 293T whole cell lysate at 50 µg
    Lane 5 : NIH3T3 whole cell lysate at 50 µg

    Developed using the ECL technique

    Predicted band size : 108 kDa
    Observed band size : 117 kDa (why is the actual band size different from the predicted?)


    Exposure time : 3 seconds
  • Detection of delta 1 Catenin by Western Blot of Immunprecipitate.
    ab72039 at 1µg/ml staining delta 1 Catenin in HeLa whole cell lysate immunoprecipitated using ab72039 at 3µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
    Detection: Chemiluminescence with exposure time of 1 second.

Anti-delta 1 Catenin antibody (ab72039) 使用論文

ab72039 has not yet been referenced specifically in any publications.

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