Anti-Decorin Binding Protein B 抗体 (ab106608)

製品の概要

  • 製品名Anti-Decorin Binding Protein B antibody
  • 製品の詳細
    Rabbit polyclonal to Decorin Binding Protein B
  • 特異性ab106608 is specific for Borrelia burgdorferi Decorin Binding Protein B. A BLAST analysis was used to suggest cross-reactivity with Decorin Binding Protein B from B. burgdorferi and B. garinii sources based on 100% homology with the immunizing sequence.
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Recombinant Fragment
    交差が予測される動物種: Other
  • 免疫原

    MBP-fusion protein corresponding to Borrelia burgdorferi Decorin Binding Protein B.

  • ポジティブ・コントロール
    • MBP-Decorin Binding Protein B fusion protein
  • 特記事項Store undiluted; dilute only prior to immediate use.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーpH: 7.20
    Preservative: 0.01% Sodium azide
    Constituents: 0.42% Potassium phosphate, 0.88% Sodium chloride
  • Concentration information loading...
  • 精製度Protein A purified
  • 特記事項(精製)ab106608 was Protein A purified and cross-adsorbed against MBP from monospecific antiserum by chromatography.
  • ポリ/モノポリクローナル
  • アイソタイプIgG

アプリケーション

Our Abpromise guarantee covers the use of ab106608 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Predicted molecular weight: 20 kDa.

ターゲット情報

  • 関連性Decorin-binding protein B, or DbpB, binds to decorin, which may mediate the adherence of B.burgdorferi to collagen fibers in skin and other tissues. Spirochetal surface adhesions mediate attachment to decorin, a major component of the host extracellular matrix enabling bacteria to colonize in mammalian tissues. The spirochete migrates from the tick midgut during feeding to its salivary glands and are thus transmitted to the mammal host. This transition may be facilitated by changes in expression of some B. burgdorferi genes. It is believed that expression of the various proteins associated with the spirochete may be regulated by the changes in tick life cycle, changes in conditions during tick feeding (such as temperature, pH, and nutrients) and/or in coordination with the course of infection of the mammal host. Borrelia burgdorferi can colonize multiple tissues, and is capable of attachment to diverse cell types. The expression of decorin-binding protein (Dbp) A and/or DbpB, two B. burgdorferi surface proteins that bind GAGs, is sufficient to convert a high-passage nonadherent B. burgdorferi strain into one that efficiently binds 293 epithelial cells.
  • 別名
    • dbpB antibody

Anti-Decorin Binding Protein B antibody 画像

  • All lanes : Anti-Decorin Binding Protein B antibody (ab106608) at 1/1000 dilution

    Lane 1 : MBP-Decorin Binding Protein B fusion protein
    Lane 2 : MBP alone

    Lysates/proteins at 0.1 µg per lane.

    Secondary
    HRP-conjugated Goat-Anti-Rabbit at 1/40000 dilution

    Predicted band size : 20 kDa

Anti-Decorin Binding Protein B antibody (ab106608) 使用論文

ab106608 has not yet been referenced specifically in any publications.

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