製品の概要
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製品名Anti-DDIT4 antibody
DDIT4 一次抗体 製品一覧 -
製品の詳細Rabbit polyclonal to DDIT4
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アプリケーション適用あり: IHC-P, WBmore details
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種交差性交差種: Mouse, Rat, Human
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免疫原
Synthetic peptide corresponding to 12 amino acids from near the center of human DDIT4 (NP_061931)
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ポジティブ･コントロール
- Human kidney tissue lysate; Mouse kidney tissue.
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Store at 4°C (stable for up to 12 months).
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バッファーPreservative: 0.02% Sodium Azide
Constituents: PBS -
Concentration information loading... -
精製度Immunogen affinity purified
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab106356 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P | Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval via the microwave method before commencing with IHC staining protocol. | |
| WB | Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 25 kDa. |
ターゲット情報
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機能Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. Promotes neuronal cell death.
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組織特異性Broadly expressed, with lowest levels in brain, skeletal muscle and intestine. Up-regulated in substantia nigra neurons from Parkinson disease patients (at protein level).
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配列類似性Belongs to the DDIT4 family.
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細胞内局在Cytoplasm.
- Information by UniProt
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参照データベース
- Entrez Gene: 54541 Human
- Entrez Gene: 74747 Mouse
- Entrez Gene: 140942 Rat
- Omim: 607729 Human
- SwissProt: Q9NX09 Human
- SwissProt: Q9D3F7 Mouse
- SwissProt: Q8VHZ9 Rat
- Unigene: 523012 Human
see all -
別名
- DDIT4 antibody
- DDIT4_HUMAN antibody
- Dig2 antibody
see all
Anti-DDIT4 antibody 画像
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Western blot - DDIT4 antibody (ab106356)Lane 1 : Anti-DDIT4 antibody (ab106356) at 0.5 µg/ml
Lane 2 : Anti-DDIT4 antibody (ab106356) at 1 µg/ml
Lane 1 : Human kidney tissue lysate
Lane 2 : Human kidney tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size : 25 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - DDIT4 antibody (ab106356)Immunohistochemistry detection of DDIT4 in paraffin embedded mouse kidney tissue section using ab106356 at 5 µg/ml.
Anti-DDIT4 antibody (ab106356) 使用論文
This product has been referenced in:
- Gupta I et al. Ascorbate attenuates pulmonary emphysema by inhibiting tobacco smoke and Rtp801-triggered lung protein modification and proteolysis. Proc Natl Acad Sci U S A 113:E4208-17 (2016). Read more (PubMed: 27382160) »
- Zhao H et al. DNA Damage-Inducible Transcript 4 Is an Innate Surveillant of Hair Follicular Stress in Vitamin D Receptor Knockout Mice and a Regulator of Wound Re-Epithelialization. Int J Mol Sci 17:N/A (2016). Read more (PubMed: 27898044) »
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"