製品の概要

  • 製品名Anti-DCXR antibody
    DCXR 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to DCXR
  • アプリケーション適用あり: IHC-P, ELISA, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Guinea pig, Hamster
  • 免疫原

    Synthetic peptide:

    GSTLPVEGGFWAC

    , corresponding to amino acids 232-244 of Human DCXR.

  • ポジティブ・コントロール
    • Hela and Human Kidney lysates.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab11800 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
ELISA
WB
  • 追加情報ELISA: 1/32000.
    WB: Use at a concentration of 0.1 - 0.5 µg/ml. Detects a band of approximately 28 kDa in Hela and Human Kidney lysates.
    IHC-P: Use at a concentration of 1 - 2 µg/ml. In paraffin embedded Human Kidney, stains membrane / cytoplasm in epithelial cells of renal glomeruli and tubules.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
    • 組織特異性Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis.
    • 関連疾患Note=The enzyme defect in pentosuria has been shown to involve L-xylulose reductase. Essential pentosuria is an inborn error of metabolism characterized by the excessive urinary excretion of the pentose L-xylulose.
    • 配列類似性Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    • 細胞内局在Membrane. Probably recruited to membranes via an interaction with phosphatidylinositol.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Carbonyl reductase 2 antibody
      • Carbonyl reductase II antibody
      • DCR antibody
      • Dcxr antibody
      • DCXR_HUMAN antibody
      • Dicarbonyl L xylulose reductase antibody
      • Dicarbonyl/ L xylulose reductase antibody
      • Dicarbonyl/L-xylulose reductase antibody
      • HCR2 antibody
      • HCRII antibody
      • Human carbonyl reductase 2 antibody
      • kiDCR antibody
      • Kidney dicarbonyl reductase antibody
      • L xylulose reductase antibody
      • L-xylulose reductase antibody
      • P34H antibody
      • PNTSU antibody
      • SDR20C1 antibody
      • Short chain dehydrogenase/reductase family 20C member 1 antibody
      • Sperm surface protein P34H antibody
      • XR antibody
      see all

    Anti-DCXR antibody 画像

    • Ab11800 staining (0.1µg/ml) of Human Kidney lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
    • Ab11800 (1ug/ml) staining human DCXR in human kidney by immunohistochemistry using paraffin embedded tissue.

      Microwaved antigen retrieval with citrate buffer, pH6, HRP-staining.

    Anti-DCXR antibody (ab11800) 使用論文

    ab11800 has not yet been referenced specifically in any publications.

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