製品の概要

  • 製品名Anti-DCUN1D1 antibody
    DCUN1D1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to DCUN1D1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 209-258 (PKDTWNLLLD FSTMIADDMS NYDEEGAWPV LIDDFVEFAR PQIAGTKSTT) of Human DCUN1D1 (NP_065691).

  • ポジティブ・コントロール
    • PANC1 cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab99195 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 30 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 関連性DCUN1D1 (DCUN1 domain-containing protein 1) contains a DUF298 domain and a UBA-like ubiquitin. Forms part of an E3 ubiquitin ligase complex for neddylation. Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation. Functions to recruit the NEDD8-charged E2 enzyme to the cullin component. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression. Defects in DCUN1D1 may be a cause of squamous cell carcinomas. Strongly overexpressed in thyroid tumors, bronchioloalveolar carcinomas, and malignant tissues of squamous cell carcinoma of the oral tongue. Not overexpressed in aggressive adrenocortical carcinomas.
  • 参照データベース
  • 別名
    • DCN1 defective in cullin neddylation 1 domain containing 1 antibody
    • DCN1 like protein 1 antibody
    • DCNL1 antibody
    • DCUN1 domain containing protein 1 antibody
    • DCUN1L1 antibody
    • Defective in cullin neddylation protein 1 like protein 1 antibody
    • RP 42 antibody
    • RP42 antibody
    • RP42 homolog antibody
    • SCCRO antibody
    • SCRO antibody
    • Squamous cell carcinoma related oncogene antibody
    • Tes 3 antibody
    • Tes3 antibody
    see all

Anti-DCUN1D1 antibody 画像

  • Anti-DCUN1D1 antibody (ab99195) at 1 µg/ml + PANC1 cell lysate at 10 µg

    Predicted band size : 30 kDa

Anti-DCUN1D1 antibody (ab99195) 使用論文

ab99195 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"