製品の概要

  • 製品名Anti-DcR1 antibody
    DcR1 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to DcR1
  • 特異性<0.2% cross-reactivity to TRAIL R2 peptide of the same region. Not likely to bind TRAIL R1 due to low sequence homology in this region. May bind TRAIL R4. May cross react to mouse TRAIL R3 as antibody binds to a similar size protein from mouse spleen on Westerns.
  • アプリケーション適用あり: ELISA, Flow Cyt, ICC, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide:

    EVPQQTVAPQQQRHSFKGEECPAGSHRSEHTC

    , corresponding to N terminal amino acids 33-64 of Human DcR1.

  • ポジティブ・コントロール
    • Human embryonic kidney cell line-293 or human T-cell line Jurkatt.
  • 特記事項TRAIL R3 = "TNF Related Apoptosis Inducing Ligand Receptor 3"

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab1674 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
Flow Cyt
ICC
WB
  • 追加情報ELISA: Use at a dilution > 1/150000.
    Flow Cyt: Use at an assay dependant dilution.
    ICC: 1/300.
    WB: 1/1000.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性DcR1 / TRAIL-R3 / TRID / LIT is one of the two putative decoy receptors identified for TRAIL, one of the members of TNF family of apoptosis inducing proteins. The other putative decoy receptor is called DcR2 / TRUNDD / TRAIL-R4. DcR1 is attached to the cell surface through glycophospholipid anchor. It has the extracellular TRAIL binding domain but lacks the cytoplasmic domain to induce apoptotic signal. Hence overexpression of DcR1 inhibits the TRAIL induced apoptosis.
    • 細胞内局在Cell Membrane and Cytoplasmic
    • 参照データベース
    • 別名
      • Antagonist decoy receptor for TRAIL/Apo 2L antibody
      • CD263 antibody
      • Cytotoxic TRAIL receptor 3 antibody
      • DCR1 antibody
      • DCR1 TNFR antibody
      • Decoy Receptor 1 antibody
      • Decoy TRAIL receptor without death domain antibody
      • LIT antibody
      • Lymphocyte inhibitor of TRAIL antibody
      • MGC149501 antibody
      • MGC149502 antibody
      • TNF related apoptosis inducing ligand receptor 3 antibody
      • TNF-re ated apoptosis inducing ligand receptor 3 antibody
      • TNFRSF10C antibody
      • TRAIL R3 antibody
      • TRAIL receptor 3 antibody
      • TRAILR3 antibody
      • TRID antibody
      • Tumor necrosis factor receptor superfamily member 10C antibody
      • Tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain antibody
      see all

    Anti-DcR1 antibody 画像

    • ab1674 recognizes a 66kDa band of expected size in Lane 1 containing TRAIL-3R-Fc protein and showed minimal or no crossreactivity to TRAIL-2R-Fc protein in Lane 2.

    Anti-DcR1 antibody (ab1674) 使用論文

    ab1674 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"