製品の概要

  • 製品名Anti-Dcp1a antibody
    Dcp1a 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Dcp1a
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide:

    C-QVLTKNKDNHN

    , corresponding to C terminal amino acids 571-581 of Dcp1a

  • ポジティブ・コントロール
    • A431 and HeLa Human lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab47998 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 75 kDa (predicted molecular weight: 63 kDa).

ターゲット情報

  • 機能Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1.
  • 組織特異性Detected in heart, brain, placenta, lung, skeletal muscle, liver, kidney and pancreas.
  • 配列類似性Belongs to the DCP1 family.
  • 細胞内局在Cytoplasm > P-body. Nucleus. Co-localizes with NANOS3 in the processing bodies (By similarity). Predominantly cytoplasmic, in processing bodies (PB). Nuclear, after TGFB1 treatment. Translocation to the nucleus depends on interaction with SMAD4.
  • Information by UniProt
  • 参照データベース
  • 別名
    • DCP1 decapping enzyme homolog A antibody
    • Dcp1a antibody
    • DCP1A_HUMAN antibody
    • Decapping enzyme hDcp1a antibody
    • Decapping mRNA 1A antibody
    • HSA275986 antibody
    • mRNA decapping enzyme 1A antibody
    • mRNA-decapping enzyme 1A antibody
    • Nbla00360 antibody
    • Putative protein product of Nbla00360 antibody
    • Smad4 interacting transcriptional co activator antibody
    • Smad4-interacting transcriptional co-activator antibody
    • Smad4-interacting transcriptional co-activator antibody
    • SMAD4IP1 antibody
    • SMIF antibody
    • Transcription factor SMIF antibody
    see all

Anti-Dcp1a antibody 画像

  • Anti-Dcp1a antibody (ab47998) at 2 µg/ml + A431 cell lysate in RIPA buffer at 35 µg

    Predicted band size : 63 kDa
    Observed band size : 75 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 48 kDa (possible non-specific binding).

Anti-Dcp1a antibody (ab47998) 使用論文

ab47998 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab47998.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"