Recombinant full length protein corresponding to Human DCK (NP_000779) produced in HEK293T cells.
HEK293T cells transfected with pCMV6-ENTRY DCK.
Dilute in PBS (pH7.3) before use. Stable for 12 months from date of receipt.
The clone number has been updated from 16E12 to OTI16E12, both clone numbers name the same clone.
Abcam is committed to meeting high standards of ethical manufacturing and as such, we will be discontinuing this product, which has been generated by the ascites method, within the next year. We are sorry for any inconvenience this may cause. If you would like help finding an alternative product, please do not hesitate to contact our scientific support team.
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/2000. Predicted molecular weight: 31 kDa.
1/100. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). Has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. It is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents.
Belongs to the DCK/DGK family.
Phosphorylated upon DNA damage, probably by ATM or ATR.