製品の概要

  • 製品名Anti-DCK antibody [2243C2]
    DCK 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [2243C2] to DCK
  • アプリケーション適用あり: WB, Dot blotmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment (N-terminal).

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at 4°C (stable for up to 12 months). Store at -20°C or -80°C.
  • バッファーPreservative: 0.05% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • 精製度Protein G purified
  • 特記事項(精製)Purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG depleted |(approximately 95%) feta bovine serum. Filtered through a 0.22 micrometer membrane.
  • ポリ/モノモノクローナル
  • クローン名2243C2
  • アイソタイプIgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab51517 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent dilution. Predicted molecular weight: 31 kDa.
Dot blot Use at an assay dependent dilution.

ターゲット情報

  • 機能Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). Has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. It is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents.
  • 配列類似性Belongs to the DCK/DGK family.
  • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • dCK antibody
    • DCK protein antibody
    • DCK_HUMAN antibody
    • Deoxycytidine kinase antibody
    • Deoxynucleoside kinase antibody
    • EC 2.7.1 antibody
    • EC 2.7.1.74 antibody
    • MGC117410 antibody
    • MGC138632 antibody
    • OTTHUMP00000219118 antibody
    • OTTHUMP00000219119 antibody
    see all

Anti-DCK antibody [2243C2] 画像

  • Anti-DCK antibody [2243C2] (ab51517) + Immunized recombinant protein

    Predicted band size : 31 kDa
    Observed band size : 31 kDa

Anti-DCK antibody [2243C2] (ab51517) 使用論文

This product has been referenced in:
  • Neschadim A  et al. Cell fate control gene therapy based on engineered variants of human deoxycytidine kinase. Mol Ther 20:1002-13 (2012). WB ; Human . Read more (PubMed: 22273576) »
  • Likar Y  et al. A new pyrimidine-specific reporter gene: a mutated human deoxycytidine kinase suitable for PET during treatment with acycloguanosine-based cytotoxic drugs. J Nucl Med 51:1395-403 (2010). WB ; Human . Read more (PubMed: 20810757) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"