製品の概要

  • 製品名Anti-DBF4 antibody
    DBF4 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to DBF4
  • 特異性ab116613 is expected to recognize both reported isoforms (NP_038754.1; NP_001177646.1).
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Rat
  • 免疫原

    Synthetic peptide:

    DKKRTEYLPAHEDRT

    with a Cysteine residue linker, corresponding to internal sequence amino acids 585-599 of Mouse DBF4 (NP_038754.1; NP_001177646.1).

  • ポジティブ・コントロール
    • Mouse and Rat Testis lysates.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーpH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 99% Tris buffered saline, 0.5% BSA
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab116613 is purified from Goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab116613 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 74 kDa.

ターゲット情報

  • 機能Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.
  • 組織特異性Highly expressed in testis and thymus. Expressed also in most cancer cells lines.
  • 配列類似性Contains 2 BRCT domains.
    Contains 1 DBF4-type zinc finger.
  • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Activator of S phase kinase antibody
    • ASK antibody
    • CHIF antibody
    • Chiffon homolog A antibody
    • DBF4 antibody
    • DBF4 homolog (S. cerevisiae) antibody
    • DBF4 homolog antibody
    • DBF4 type zinc finger containing protein 1 antibody
    • DBF4 zinc finger A antibody
    • DBF4 zinc finger antibody
    • DBF4, S. cerevisiae, homolog of antibody
    • DBF4-type zinc finger-containing protein 1 antibody
    • DBF4A antibody
    • DBF4A_HUMAN antibody
    • Dumbbell former 4, S. cerevisiae, homolog of antibody
    • OTTHUMP00000161661 antibody
    • Protein DBF4 homolog A antibody
    • ZDBF1 antibody
    • Zinc finger, DBF-type containing 1 antibody
    see all

Anti-DBF4 antibody 画像

  • Anti-DBF4 antibody (ab116613) at 1 µg/ml + Mouse testis lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 74 kDa

Anti-DBF4 antibody (ab116613) 使用論文

ab116613 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab116613.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"