製品の概要

  • 製品名Anti-DAZ2 antibody
    DAZ2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to DAZ2
  • アプリケーション適用あり: WB, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant protein fragment corresponding to a region within amino acids 1 - 207 of Human DAZ2 (NP_065096).

  • ポジティブ・コントロール
    • WB: 293T, A431, HeLa, MOLT4 and Raji cell lysate IF: HeLa cells

法規制情報

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG

アプリケーション

Our Abpromise guarantee covers the use of ab97772 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 63 kDa.
ICC/IF 1/100 - 1/200.

ターゲット情報

  • 機能RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation.
  • 組織特異性Testis specific.
  • 関連疾患Defects in DAZ2 may be a cause of spermatogenic failure Y-linked type 2 (SPGFY2) [MIM:415000]. It is a disorder resulting in the absence (azoospermia) or reduction (oligozoospermia) of sperm in the semen, leading to male infertility. Note=AZFc deletions in the Yq11.23 region including the DAZ genes are the most common known genetic cause of human male infertility.
  • 配列類似性Belongs to the RRM DAZ family.
    Contains 15 DAZ-like domains.
    Contains 1 RRM (RNA recognition motif) domain.
  • ドメインThe DAZ-like repeats are essential and mediate the interaction with DAZAP1 and DAZAP2.
  • 細胞内局在Cytoplasm. Nucleus. Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis.
  • Information by UniProt
  • 参照データベース
  • 別名
    • DAZ2 antibody
    • DAZ2_HUMAN antibody
    • DAZ3 antibody
    • Deleted in azoospermia 2 antibody
    • Deleted in azoospermia protein 2 antibody
    • Deleted in azoospermia protein 3 antibody
    • MGC126442 antibody
    • pDP1678 antibody
    see all

Anti-DAZ2 antibody 画像

  • Anti-DAZ2 antibody (ab97772) at 1/1000 dilution + MOLT4 whole cell lysate at 30 µg

    Predicted band size : 63 kDa
  • ab97772, at a 1/200 dilution, staining DAZ2 in paraformaldehyde-fixed HeLa cells by Immunofluorescence analysis. Right image is merged with a DNA probe.

Anti-DAZ2 antibody (ab97772) 使用論文

ab97772 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab97772.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"