製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to DARPP32
  • アプリケーション
    適用あり: IHC-FoFr, IHC-P, WBmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide (Human) conjugated to KLH.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab18551 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-FoFr Use at an assay dependent concentration. PubMed: 20207227
IHC-P 1/50.
WB 1/1000. Predicted molecular weight: 23 kDa.

ターゲット情報

  • 機能
    Inhibitor of protein-phosphatase 1.
  • 配列類似性
    Belongs to the protein phosphatase inhibitor 1 family.
  • 翻訳後修飾
    Dopamine- and cyclic AMP-regulated neuronal phosphoprotein.
    Phosphorylation of Thr-34 is required for activity.
  • 細胞内局在
    Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • DARPP 32 antibody
    • DARPP-32 antibody
    • Dopamine and cAMP regulated neuronal phosphoprotein 32 antibody
    • Dopamine and cAMP regulated neuronal phosphoprotein antibody
    • Dopamine and cAMP regulated phosphoprotein antibody
    • Dopamine and cAMP regulated phosphoprotein DARPP 32 antibody
    • Dopamine and cAMP regulated phosphoprotein DARPP32 antibody
    • Dopamine- and cAMP-regulated neuronal phosphoprotein antibody
    • FLJ20940 antibody
    • IPPD antibody
    • Neuronal phosphoprotein DARPP 32 antibody
    • PPP1R1B antibody
    • PPR1B_HUMAN antibody
    • Protein phosphatase 1 regulatory (inhibitor) subunit 1B antibody
    • Protein phosphatase 1 regulatory inhibitor subunit 1B antibody
    • Protein phosphatase 1 regulatory subunit 1B antibody
    see all

参考文献

This product has been referenced in:
  • Maheshwari M  et al. Deficiency of Ube3a in Huntington's disease mice brain increases aggregate load and accelerates disease pathology. Hum Mol Genet N/A:N/A (2014). Mouse . Read more (PubMed: 25027318) »
  • Martínez-Cerdeño V  et al. Embryonic MGE precursor cells grafted into adult rat striatum integrate and ameliorate motor symptoms in 6-OHDA-lesioned rats. Cell Stem Cell 6:238-50 (2010). IHC-FoFr ; Rat . Read more (PubMed: 20207227) »

See all 2 Publications for this product

レビューと Q&A

The immunogen for ab18551 has only a small portion of the eptiope present in isoform 2. It is highly unlikely that this antibody will bind to isoform 2, but we have not performed any testing to confirm this.


As I mentioned in my previo...

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Thank you for your enquiry. We have antibodies against both the non-phosphorylated and phospho T75 forms of DARPP32. They are detailed as follows with their associated applications. ab18551 DARPP32 antibody, Rabbit Polyclonal. ELISA, IHC-P, WB ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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