製品の概要

  • 製品名Anti-DAB2 antibody
    DAB2 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to DAB2
  • アプリケーション適用あり: WB, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length protein, corresponding to amino acids 1-770 of Human DAB2 (AAH03064.1).

  • ポジティブ・コントロール
    • Human liver tissue, HeLa cell, transfected 293T cell lysates and HeLa cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab88590 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 82 kDa.
ICC/IF Use a concentration of 10 µg/ml.

ターゲット情報

  • 関連性DAB2 is a component of the CSF1 signal transduction pathway. DAB2 mRNA is expressed in normal ovarian epithelial cells but is down regulated or absent from ovarian carcinoma cell lines. The down regulation of DAB2 may play an important role in ovarian carcinogenesis. This gene was initially named DOC2 (for Differentially expressed in Ovarian Cancer) and is distinct from the DOC2A and DOC2B genes (for double C2 like domains, alpha and beta).
  • 細胞内局在Cytoplasmic vesicle; clathrin coated vesicle; clathrin coated vesicle membrane. Cell membrane; coated pit; clathrin coated pit. Note: Colocalizes with large insert containing isoforms of MYO6 at clathrin coated pits/vesicles.
  • 参照データベース
  • 別名
    • DAB 2 antibody
    • Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) antibody
    • DAB2 antibody
    • Differentially expressed in ovarian cancer 2 antibody
    • Differentially expressed protein 2 antibody
    • Disabled (Drosophila) homolog 2 (mitogen responsive phosphoprotein) antibody
    • Disabled homolog 2 antibody
    • Disabled homolog 2 mitogen responsive phosphoprotein (Drosophila) antibody
    • Disabled homolog 2 mitogen responsive phosphoprotein antibody
    • Disabled, Drosophila, homolog of, 2 antibody
    • DOC 2 antibody
    • DOC2 antibody
    • FLJ26626 antibody
    • Mitogen responsive phosphoprotein antibody
    see all

Anti-DAB2 antibody 画像

  • Anti-DAB2 antibody (ab88590) at 1 µg/ml + human liver tissue lysate at 50 µg
    Developed using the ECL technique

    Predicted band size : 82 kDa
    Observed band size : 82 kDa
  • Anti-DAB2 antibody (ab88590) at 1 µg/ml + HeLa cell lysate at 50 µg
    Developed using the ECL technique

    Predicted band size : 82 kDa
    Observed band size : 100 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 55 kDa. We are unsure as to the identity of these extra bands.
  • All lanes : Anti-DAB2 antibody (ab88590) at 1 µg/ml

    Lane 1 : cell lysate from DAB2 transfected 293T cells
    Lane 2 : cell lysate from non transfected 293T cells

    Lysates/proteins at 25 µg per lane.

    Developed using the ECL technique

    Predicted band size : 82 kDa
    Observed band size : 95 kDa (why is the actual band size different from the predicted?)
  • ab88590 at 10 µg/ml detecting DAB2 in HeLa cells by immunofluorescence.

Anti-DAB2 antibody (ab88590) 使用論文

ab88590 has not yet been referenced specifically in any publications.

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