Rabbit polyclonal to Dab1 (phospho Y232)
This antibody detects endogenous levels of Dab1 only when phosphorylated at tyrosine 232.
Synthesized phosphopeptide derived from human Dab1 around the phosphorylation site of tyrosine 232 (G-V-Y
Extracts from LOVO cells.
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS, 150mM Sodium chloride, pH 7.4
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Immunogen affinity purified
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 67 kDa (predicted molecular weight: 67 kDa).
Adapter molecule functioning in neural development. May regulate SIAH1 activity.
Contains 1 PID domain.
The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins.
Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling.
Information by UniProt
Dab 1 antibody
Dab reelin signal transducer 1 antibody
Dab, reelin signal transducer, homolog 1 (Drosophila) antibody
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