製品の概要

  • 製品名Anti-Dab1 antibody [EP2248Y]
    Dab1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EP2248Y] to Dab1
  • アプリケーション適用あり: WBmore details
    適用なし: Flow Cyt,ICC/IF,IHC-P or IP
  • 種交差性
    交差種: Mouse, Rat
  • 免疫原

    A synthetic peptide corresponding to residues surrounding serine 491 of human Dab1.

  • ポジティブ・コントロール
    • Rat brain lysate.
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

     

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Human: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab68461 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: 1/1000 - 1/2000. Detects a band of approximately 70 kDa (predicted molecular weight: 67 kDa).

    Is unsuitable for Flow Cyt, ICC/IF, IHC-P or IP.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Adapter molecule functioning in neural development. May regulate SIAH1 activity.
    • 配列類似性Contains 1 PID domain.
    • ドメインThe PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins.
    • 翻訳後修飾Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Dab 1 antibody
      • Dab reelin signal transducer 1 antibody
      • Dab, reelin signal transducer, homolog 1 (Drosophila) antibody
      • Dab1 antibody
      • DAB1_HUMAN antibody
      • Disabled homolog 1 antibody
      • Disabled homolog 1 Drosophila antibody
      • Scm antibody
      • Scr antibody
      • Scrambler antibody
      • Yot antibody
      • Yotari antibody
      see all

    Anti-Dab1 antibody [EP2248Y] 画像

    • Anti-Dab1 antibody [EP2248Y] (ab68461) at 1/2000 dilution + Rat brain lysate at 10 µg

      Secondary
      HRP conjugated Goat anti Rabbit. at 1/2000 dilution

      Predicted band size : 67 kDa
      Observed band size : 70 kDa (why is the actual band size different from the predicted?)

    Anti-Dab1 antibody [EP2248Y] (ab68461) 使用論文

    ab68461 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab68461.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"