Anti-Cytokeratin AE3 抗体 [CK 211 (AE3)] (ab115983)

製品の概要

  • 製品名Anti-Cytokeratin AE3 antibody [CK 211 (AE3)]
  • 製品の詳細
    Mouse monoclonal [CK 211 (AE3)] to Cytokeratin AE3
  • 特異性ab115983 reacts Cytokeratins 1, 2, 3, 4, 5 6 and 8.
  • アプリケーション適用あり: IHC-P, IHC-Fr, ICCmore details
  • 種交差性
    交差種: Mouse, Rat, Rabbit, Chicken, Cow, Human, Pig, Monkey
  • 免疫原

    Human epidermal keratin

  • ポジティブ・コントロール
    • Human skin tissue and lung carcinoma tissue.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーpH: 7.40
    Preservative: 0.05% Sodium azide
    Constituents: 98% PBS, 1% BSA
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノモノクローナル
  • クローン名CK 211 (AE3)
  • アイソタイプIgG1
  • 軽鎖の種類kappa
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab115983 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/50 - 1/100. An antigen retriever like trypsin is required.
IHC-Fr 1/50 - 1/100.
ICC Use at an assay dependent concentration.

ターゲット情報

  • 組織特異性Cornea specific.
  • 関連疾患Defects in KRT3 are a cause of Meesmann corneal dystrophy (MECD) [MIM:122100]; also abbreviated as MCD and known as juvenile epithelial corneal dystrophy of Meesmann. MECD is an autosomal dominant disease that causes fragility of the anterior corneal epithelium. Patients are usually asymptomatic until adulthood when rupture of the corneal microcysts may cause erosions, producing clinical symptoms such as photophobia, contact lens intolerance and intermittent diminution of visual acuity. Rarely, subepithelial scarring causes irregular corneal astigmatism and permanent visual impairment. Histological examination shows a disorganized and thickened epithelium with widespread cytoplasmic vacuolation and numerous small, round, debris-laden intraepithelial cysts.
  • 配列類似性Belongs to the intermediate filament family.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 65 kDa cytokeratin antibody
    • CK-3 antibody
    • CK3 antibody
    • Cytokeratin-3 antibody
    • FLJ95909 antibody
    • K2C3_HUMAN antibody
    • K3 antibody
    • Keratin antibody
    • Keratin-3 antibody
    • KRT3 antibody
    • type II cytoskeletal 3 antibody
    • Type-II keratin Kb3 antibody
    see all

Anti-Cytokeratin AE3 antibody [CK 211 (AE3)] (ab115983) 使用論文

ab115983 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"