Anti-Cytokeratin 9 抗体 [Ks9.70/Ks9.216] (ab19124)

製品の概要

  • 製品名Anti-Cytokeratin 9 antibody [Ks9.70/Ks9.216]
    Cytokeratin 9 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [Ks9.70/Ks9.216] to Cytokeratin 9
  • 特異性Specifically reactive in the middle/upper suprabasal layers (stratum spinosum/granulosum) of the epidermis of palm and sole. CK9 can be detected in primary cultures of palmoplantar keratinocytes when they shift to differentiation-promoting conditions and grow stratified (upper cells). CK9 has not been found in epithelial cells of other stratified epithelia such as oesophagus or complex epithelia (e.g. urothelium) or in ductal or simple epithelia. Negative tissues include: muscle, liver and duodenum.
  • アプリケーション適用あり: WB, IHC-Fr, ICC/IF, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide:

    IETYHNLLEG GQEDFESSGA GKIGLGGR

    , corresponding to amino acids 450 - 477 of Human Cytokeratin 9. Synthetic peptide: RQFSSSYLTS GGGGGGGLGS GGSIR, corresponding to amino acids 4 - 28 of Human Cytokeratin 9.

  • 特記事項Isotypes IgG1 (Ks9.70) and IgG3 (Ks9.216)


    The antibody cocktail is an excellent new tool to characterize primary cultures of keratinocytes/skin transplants for application in burn treatment.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.02% Sodium azide
    Constituent: Tissue culture supernatant
  • 精製度Tissue culture supernatant
  • 一次抗体 備考The antibody cocktail is an excellent new tool to characterize primary cultures of keratinocytes/skin transplants for application in burn treatment.
  • ポリ/モノモノクローナル
  • クローン名Ks9.70/Ks9.216
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab19124 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent concentration. Predicted molecular weight: 62 kDa.
IHC-Fr 1/20.
ICC/IF 1/10.
IHC-P 1/20. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Perform heat mediated antigen retrieval (microwave method) before commencing with IHC staining protocol; in some cases protease digestion is most suitable.

ターゲット情報

  • 機能May serve an important special function either in the mature palmar and plantar skin tissue or in the morphogenetic program of the formation of these tissues. Plays a role in keratin filament assembly.
  • 組織特異性Expressed in the terminally differentiated epidermis of palms and soles.
  • 関連疾患Defects in KRT9 are a cause of palmoplantar keratoderma epidermolytic (EPPK) [MIM:144200]; also abbreviated as EHPPK. EPPK is a dermatological disorder characterized by diffuse thickening of the epidermis on the entire surface of palms and soles sharply bordered with erythematous margins. Some patients may present with knuckle pads, thick pads of skin appearing over the proximal phalangeal joints.
  • 配列類似性Belongs to the intermediate filament family.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CK 9 antibody
    • CK-9 antibody
    • Cytokeratin 9 antibody
    • Cytokeratin-9 antibody
    • Cytokeratin9 antibody
    • EPPK antibody
    • K1C9_HUMAN antibody
    • K9 antibody
    • Keratin 9 antibody
    • Keratin antibody
    • Keratin type I cytoskeletal 9 antibody
    • Keratin-9 antibody
    • Keratin9 antibody
    • KRT 9 antibody
    • Krt9 antibody
    • Spermatid Perinuclear Ring Manchette Protein K9 antibody
    • type I cytoskeletal 9 antibody
    see all

Anti-Cytokeratin 9 antibody [Ks9.70/Ks9.216] (ab19124) 使用論文

ab19124 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"