Anti-Cytokeratin 9 抗体 [Ks9.70/Ks9.216] (ab19124)
Key features and details
- Mouse monoclonal [Ks9.70/Ks9.216] to Cytokeratin 9
- Suitable for: IHC-P, WB, IHC-Fr, ICC/IF
- Reacts with: Human
- Isotype: IgG1
製品の概要
-
製品名
Anti-Cytokeratin 9 antibody [Ks9.70/Ks9.216]
Cytokeratin 9 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [Ks9.70/Ks9.216] to Cytokeratin 9 -
由来種
Mouse -
特異性
Specifically reactive in the middle/upper suprabasal layers (stratum spinosum/granulosum) of the epidermis of palm and sole. CK9 can be detected in primary cultures of palmoplantar keratinocytes when they shift to differentiation-promoting conditions and grow stratified (upper cells). CK9 has not been found in epithelial cells of other stratified epithelia such as oesophagus or complex epithelia (e.g. urothelium) or in ductal or simple epithelia. Negative tissues include: muscle, liver and duodenum. -
アプリケーション
適用あり: IHC-P, WB, IHC-Fr, ICC/IFmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide:
IETYHNLLEG GQEDFESSGA GKIGLGGR
, corresponding to amino acids 450 - 477 of Human Cytokeratin 9. Synthetic peptide: RQFSSSYLTS GGGGGGGLGS GGSIR, corresponding to amino acids 4 - 28 of Human Cytokeratin 9. -
特記事項
Isotypes IgG1 (Ks9.70) and IgG3 (Ks9.216)The antibody cocktail is an excellent new tool to characterize primary cultures of keratinocytes/skin transplants for application in burn treatment.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.3
Preservative: 0.02% Sodium azide
Constituent: Tissue culture supernatant -
Concentration information loading...
-
精製度
Tissue culture supernatant -
一次抗体 備考
The antibody cocktail is an excellent new tool to characterize primary cultures of keratinocytes/skin transplants for application in burn treatment. -
ポリ/モノ
モノクローナル -
クローン名
Ks9.70/Ks9.216 -
アイソタイプ
IgG1 -
研究分野
関連製品
-
Compatible Secondaries
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab19124の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
IHC-P |
Use at an assay dependent concentration.
|
|
WB |
Use at an assay dependent concentration.
|
|
IHC-Fr |
Use at an assay dependent concentration.
|
|
ICC/IF |
Use at an assay dependent concentration.
|
特記事項 |
---|
IHC-P
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
IHC-Fr
Use at an assay dependent concentration. |
ICC/IF
Use at an assay dependent concentration. |
ターゲット情報
-
機能
May serve an important special function either in the mature palmar and plantar skin tissue or in the morphogenetic program of the formation of these tissues. Plays a role in keratin filament assembly. -
組織特異性
Expressed in the terminally differentiated epidermis of palms and soles. -
関連疾患
Defects in KRT9 are a cause of palmoplantar keratoderma epidermolytic (EPPK) [MIM:144200]; also abbreviated as EHPPK. EPPK is a dermatological disorder characterized by diffuse thickening of the epidermis on the entire surface of palms and soles sharply bordered with erythematous margins. Some patients may present with knuckle pads, thick pads of skin appearing over the proximal phalangeal joints. -
配列類似性
Belongs to the intermediate filament family. - Information by UniProt
-
参照データベース
- Entrez Gene: 3857 Human
- Omim: 607606 Human
- SwissProt: P35527 Human
- Unigene: 654569 Human
-
別名
- CK 9 antibody
- CK-9 antibody
- Cytokeratin 9 antibody
see all
プロトコール
データシートおよび資料
-
Datasheet download
参考文献 (0)
ab19124 は論文での使用が確認できていません。