Anti-Cytokeratin 8 抗体 [SB37b] (HRP) (ab87012)

製品の概要

  • 製品名Anti-Cytokeratin 8 antibody [SB37b] (HRP)
    Cytokeratin 8 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [SB37b] to Cytokeratin 8 (HRP)
  • 標識HRP
  • 特異性ab87012 reacts specifically with cytokeratin 8 and the recombinant C terminal cytokeratin 8.
  • アプリケーション適用あり: ICC/IF, WB, ELISA, IHC-Frmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant C terminal fragment of Cytokeratin 8

  • ポジティブ・コントロール
    • HT29 and HCC38 cell lines. HT29 and HCC38 cell lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab87012 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use at an assay dependent dilution.
WB 1/5000 - 1/10000. Predicted molecular weight: 54 kDa.
ELISA Use at an assay dependent dilution.
IHC-Fr 1/1000 - 1/2000.

ターゲット情報

  • 機能Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
  • 組織特異性Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity.
  • 関連疾患Cirrhosis
  • 配列類似性Belongs to the intermediate filament family.
  • 翻訳後修飾Phosphorylation on serine residues is enhanced during EGF stimulation and mitosis. Ser-74 phosphorylation plays an important role in keratin filament reorganization.
    O-glycosylated. O-GlcNAcylation at multiple sites increases solubility, and decreases stability by inducing proteasomal degradation.
    O-glycosylated (O-GlcNAcylated), in a cell cycle-dependent manner.
  • 細胞内局在Cytoplasm. Nucleus, nucleoplasm. Nucleus matrix.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CARD2 antibody
    • CK 8 antibody
    • CK-8 antibody
    • CK8 antibody
    • CYK8 antibody
    • CYKER antibody
    • Cytokeratin endo A antibody
    • Cytokeratin-8 antibody
    • DreK8 antibody
    • EndoA antibody
    • K2C8 antibody
    • K2C8_HUMAN antibody
    • K8 antibody
    • Keratin 8 antibody
    • Keratin type II cytoskeletal 8 antibody
    • Keratin, type II cytoskeletal 8 antibody
    • Keratin-8 antibody
    • KO antibody
    • Krt 2.8 antibody
    • KRT8 antibody
    • MGC118110 antibody
    • MGC174782 antibody
    • MGC53564 antibody
    • MGC85764 antibody
    • sb:cb186 antibody
    • Type-II keratin Kb8 antibody
    see all

Anti-Cytokeratin 8 antibody [SB37b] (HRP) (ab87012) 使用論文

ab87012 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"