Anti-Cytokeratin 8 抗体 [SB37b] (FITC) (ab87010)

製品の概要

  • 製品名
    Anti-Cytokeratin 8 antibody [SB37b] (FITC)
    Cytokeratin 8 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [SB37b] to Cytokeratin 8 (FITC)
  • 標識
    FITC. Ex: 493nm, Em: 528nm
  • 特異性
    ab87010 reacts specifically with cytokeratin 8 and the recombinant C terminal of cytokeratin 8.
  • アプリケーション
    適用あり: ICC/IF, ELISA, WB, IHC-Frmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant C terminal fragment of Cytokeratin 8

  • ポジティブ・コントロール
    • HT29 and HCC38 cells. HT29 and HCC38 cell lysates.
  • 特記事項

    Abcam is committed to meeting high standards of ethical manufacturing and has decided to discontinue this product by June 2019 as it has been generated by the ascites method. We are sorry for any inconvenience this may cause.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab87010 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use at an assay dependent dilution.
ELISA Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Predicted molecular weight: 54 kDa.
IHC-Fr Use a concentration of 10 µg/ml.

ターゲット情報

  • 機能
    Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
  • 組織特異性
    Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity.
  • 関連疾患
    Cirrhosis
  • 配列類似性
    Belongs to the intermediate filament family.
  • 翻訳後修飾
    Phosphorylation on serine residues is enhanced during EGF stimulation and mitosis. Ser-74 phosphorylation plays an important role in keratin filament reorganization.
    O-glycosylated. O-GlcNAcylation at multiple sites increases solubility, and decreases stability by inducing proteasomal degradation.
    O-glycosylated (O-GlcNAcylated), in a cell cycle-dependent manner.
  • 細胞内局在
    Cytoplasm. Nucleus, nucleoplasm. Nucleus matrix.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CARD2 antibody
    • CK 8 antibody
    • CK-8 antibody
    • CK8 antibody
    • CYK8 antibody
    • CYKER antibody
    • Cytokeratin endo A antibody
    • Cytokeratin-8 antibody
    • DreK8 antibody
    • EndoA antibody
    • K2C8 antibody
    • K2C8_HUMAN antibody
    • K8 antibody
    • Keratin 8 antibody
    • Keratin type II cytoskeletal 8 antibody
    • Keratin, type II cytoskeletal 8 antibody
    • Keratin-8 antibody
    • KO antibody
    • Krt 2.8 antibody
    • KRT8 antibody
    • MGC118110 antibody
    • MGC174782 antibody
    • MGC53564 antibody
    • MGC85764 antibody
    • sb:cb186 antibody
    • Type-II keratin Kb8 antibody
    see all

Anti-Cytokeratin 8 antibody [SB37b] (FITC) 画像

  • ab87010, at 10 µg/ml, staining Cytokeratin 8 in frozen sections of the HCC38 pancreatic carcinoma cell line by Immunohistochemistry. Positive cells are viewed by fluorescence microscopy.

Anti-Cytokeratin 8 antibody [SB37b] (FITC) (ab87010) 使用論文

ab87010 has not yet been referenced specifically in any publications.

Product Wall


The source of the antibody considers the F:P ratio to be proprietary.
They have not measured the isoelectric point (pI) of this particular antibody, but some studies indicate that most mouse monoclonal antibodies fall in the range of 6.4 - 7.6...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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